Development of web-based CT dose calculator for patient-specific organ doses depending on age and physical size

开发了WAZA-ARI计算器，通过利用体素幻象作为标准的日本物理尺寸来估计CT扫描的器官剂量。本研究旨在确定校正系数，以估计在日常临床实践中包括儿童在内的任何大小的患者的器官剂量。佛罗里达大学的幽灵被用于儿童的剂量。通过改变软组织的体积产生不同大小的幻影，瘦患者的BMI物理尺寸偏差比标准低2倍，胖患者的BMI物理尺寸偏差比标准高2 ~ 5倍。此外，我们根据不同大小患者的CT图像构建体素幻象，模拟CT检查中的辐射传输，通过蒙特卡罗模拟获得器官剂量。结果表明，有效直径与器官剂量之间的线性关系可以预测患者特异性器官剂量。我们完成了可以考虑任何尺寸和年龄的WAZA-ARI 2。

The WAZA-ARI calculator was developed to estimate organ doses from CT scans by utilizing the voxel phantoms as the standard Japanese physical size. This study aimed to determine correction coefficients to estimate organ doses to patients of any size attended to in daily clinical practice including children. Florida University phantoms were used for the dose to children. Different size phantoms were developed by modifying the volume of soft tissues where the deviation of physical sizes in BMI was 2 times lower for thin patients and 2 or 5 times higher for fat patients than the standard. Furthermore, we constructed voxel phantoms based on the CT images of patients of different size and simulated radiation transport in CT examinations to obtain organ doses using Monte Carlo simulation. The results show the linear relationship between effective diameter and organ dose can predict patient-specific organ doses. We completed the WAZA-ARI 2 that can take any sizes and age into account.