Development of web-based CT dose calculator for patient-specific organ doses depending on age and physical size

WAZA-ARI计算器的开发是为了通过利用体素体模作为标准日本物理尺寸来估计CT扫描的器官剂量。本研究旨在确定校正系数，以估计在日常临床实践中接受治疗的任何体型患者（包括儿童）的器官剂量。使用佛罗里达大学的药物模型对儿童进行给药。通过修改软组织体积，开发出不同尺寸的体模，其中瘦患者的BMI物理尺寸偏差比标准低2倍，胖患者的BMI物理尺寸偏差比标准高2或5倍。在此基础上，我们根据不同大小的患者的CT图像构建体素体模，并利用蒙特卡罗模拟方法模拟CT检查中的辐射输运，以获得器官剂量。结果表明，有效直径与器官剂量之间的线性关系可以预测患者的特定器官剂量。我们完成了WAZA-ARI 2，可以考虑任何尺寸和年龄。

The WAZA-ARI calculator was developed to estimate organ doses from CT scans by utilizing the voxel phantoms as the standard Japanese physical size. This study aimed to determine correction coefficients to estimate organ doses to patients of any size attended to in daily clinical practice including children. Florida University phantoms were used for the dose to children. Different size phantoms were developed by modifying the volume of soft tissues where the deviation of physical sizes in BMI was 2 times lower for thin patients and 2 or 5 times higher for fat patients than the standard. Furthermore, we constructed voxel phantoms based on the CT images of patients of different size and simulated radiation transport in CT examinations to obtain organ doses using Monte Carlo simulation. The results show the linear relationship between effective diameter and organ dose can predict patient-specific organ doses. We completed the WAZA-ARI 2 that can take any sizes and age into account.