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Investigation into epigenetic regulatory mechanism by microRNA in carcinogenesis

Investigation into epigenetic regulatory mechanism by microRNA in carcinogenesis
microRNA在癌变中的表观遗传调控机制研究
批准号:
23592015
负责人:
TAKAMORI Hiroshi
金额:
$3.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
EZH2 is associated with the accelerated cell proliferation in pancreatic IPMN via the downregulation of p27Kip1 by analyzing surgically resected pancreatic IPMN. On the other hand, Transfection of pre-miR-101 into pancreatic cell line decreased EZH2 expression in mRNA and protein level. Expression of miR-101 was significantly lower in malignant IPMN than benign IPMN. These result shows miR-101 regulate EZH2 expression in pancreatic IPMN.
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会议论文
Feasibility of Delta-Shaped Anastomoses in Totally Laparoscopic Distal Gastrectomy
三角吻合在全腹腔镜远端胃切除术中的可行性
DOI: 10.1159/000332850
发表时间: 2011
期刊: Eur Surg Res
影响因子: 1.6
作者: [Oki E., et al]
通讯作者: et al
DOI: 10.1245/s10434-011-2068-6
发表时间: 2012-07-01
期刊: ANNALS OF SURGICAL ONCOLOGY
影响因子: 3.7
作者: [Nakahara, Osamu, Takamori, Hiroshi, Baba, Hideo]
通讯作者: Baba, Hideo
DOI: 10.1097/sle.0b013e318219a66b
发表时间: 2011-06-01
期刊: SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES
影响因子: 1
作者: [Oki, Eiji, Sakaguchi, Yoshihisa, Maehara, Yoshihiko]
通讯作者: Maehara, Yoshihiko
Analysis of the interaction between pancreatic stromal cells and adenocarcinoma via complement component 5a receptor
  • 批准号:
    18K08623
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.91万
  • 财政年份:
    2018
  • 负责人:
    TAKAMORI Hiroshi
  • 依托单位:
Clinical implication of Farnesoid-X-receptor agonist in liver regeneration after hepatectomy
  • 批准号:
    26462047
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.16万
  • 财政年份:
    2014
  • 负责人:
    TAKAMORI Hiroshi
  • 依托单位:
Is it possible to develop radical treatment of cancer based on cancer stem cell theory?
  • 批准号:
    20591634
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.0万
  • 财政年份:
    2008
  • 负责人:
    TAKAMORI Hiroshi
  • 依托单位:
System Analytic Approach to Financial Technology, Management and Governance
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