The study of tissue protection and cell implantation effects by adipose tissue derived stromal cells for future usage in damaged or transplanted lung

在启动研究中，我们采用肝门结扎法建立了大鼠脑缺血再灌注模型。利用该模型，我们可以证明PARP-1抑制剂对组织损伤有保护作用。这项研究发表在《移植》杂志上。在脂肪组织来源的基质细胞的研究中，我们建立了大鼠肺移植模型，并将其用于预防组织排斥反应。有趣的是，脂肪组织来源的基质细胞增强了免疫抑制的效果。

In the starting up study, we established rat ischemia-reperfusion model using hilar clumping. Using the model, we could show that PARP-1 inhibitor prevent the tissue injury. The study was accepted in the journal of Transplantation. In the study of adipose tissue derived stromal cells, we established rat lung transplantation model and used the cells to prevent tissue rejection. Interestingly, adipose tissue derived stromal cells enhanced the effects of immunosuppressant.