The study of ECM fixation for Ti implant with an artificial periodontal membrane

人工牙周膜ECM固定钛种植体的研究

• 批准号: 23592897
• 负责人: SAITOH Setsuo
• 金额: $ 3.08万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592897/
• 关键词: チタンインプラント; 歯根膜; 表面処理; 金蒸着; アルカンチオール; 歯根膜付きチタンインプラント; ぬれ性; レーザー表面加工

A new method to enhance the biofunctionalization of Ti materials was developed by the immersion of Au-sputtered titanium plates into a solution of alkanethiol with a carboxy group end (HS-C11-COOH). X-ray photoelectron spectroscopy (XPS) analysis showed that the gold content increased with the Au sputtering time. The content of the characteristic alkanethiol elements (S, C, and O) in the immersed Ti specimens increased with the Au sputtering time, which indicates that the binding of alkanethiol molecules is enhanced by the Au modification on the Ti surface. Qualitative analysis of XPS (Au-S, COO-, and OH- species) and FTIR (peaks assignable to an aliphatic carboxylic acid) spectra for the sample after immersion also supported this. A strong positive correlation between the S and Au content confirms that Au sputtering is an effective method to control the alkanethiol treatment of Ti substrates.

提出了一种新的钛基材料生物功能化的方法，即将溅射金的钛片浸入到带有羧基末端的烷基乙醇（HS-C11-COOH）溶液中。X射线光电子能谱（XPS）分析表明，随着Au溅射时间的延长，薄膜中金含量增加。随着Au溅射时间的延长，Ti样品中的特征元素（S、C和O）的含量增加，表明Au修饰增强了Ti表面上烷基醚分子的结合。浸泡后样品的XPS（Au-S、COO-和OH-物质）和FTIR（可归属于脂肪族羧酸的峰）光谱的定性分析也支持这一点。S和Au含量之间的强正相关性证实了Au溅射是控制Ti衬底的烷醚化处理的有效方法。

项目成果

チタン表面のレーザー加工と表面形状の解析

钛表面激光加工及表面形状分析

• 发表时间: 2013
• 作者: 橋本正則;戸島洋和;長野二三;井田有亮;遠藤一彦;齋藤設雄
• 通讯作者: 齋藤設雄

Effect of gold deposition onto titanium on the adsorption of alkanethiols as the protein linker functionalizing the metal surface.

• DOI: 10.4012/dmj.2013-182
• 发表时间: 2014-01
• 期刊: Dental materials journal
• 影响因子: 2.5
• 作者: S. Saitoh;T. Nezu;K. Sasaki;M. Taira;H. Miura

チタンへの金蒸着がチオール化合物の付着に及ぼす影響

钛上金气相沉积对硫醇化合物附着力的影响

• 发表时间: 2011
• 作者: Yoshida M;Okubo N;Chosa N;Hasegawa T;Ibi M;Kamo M;Kyakumoto S;Ishisaki A.;齋藤設雄
• 通讯作者: 齋藤設雄