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Molecular analyses of genes related to cognitive abilities.

Molecular analyses of genes related to cognitive abilities.
与认知能力相关的基因的分子分析。
批准号：
23650136
负责人：
KOBAYASHI Kazuhiro
金额：
$2.58万
依托单位：
Kobe University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Challenging Exploratory Research
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 --
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23650136/
关键词：
脳認知科学ゲノム脳科学エピジェネティクス認知知能精神発達遅滞CNVマイクロアレイ

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中文摘要
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英文摘要
We divided the inbred mice into high and low performance groups by behavioral analysis, and we identified some gene sets that showed differential expression between the groups. Using monozygotic twins discordant for IQ scores, we also identified some gene sets that expressed differentially between siblings and one gene that showed differential DNA methylation status. In patients with mental retardation, we detected several known duplication or deletion syndromes and unknown copy number changes, CNVs. These genes and CNVs could be associated with cognitive abilities.
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会议论文
Genome-wide DNA methylation and gene expression analyses of monozygotic twins discordant for intelligence levels.
DOI： 10.1371/journal.pone.0047081
发表时间： 2012
期刊： PloS one
影响因子： 3.7
作者： [Yu CC, Furukawa M, Kobayashi K, Shikishima C, Cha PC, Sese J, Sugawara H, Iwamoto K, Kato T, Ando J, Toda T]
通讯作者： Toda T
Heterocycle synthesis utilizing ortho-fuctionalized benzyl azides
  • 批准号：
    26410051
  • 项目类别：
    Grant-in-Aid for Scientific Research (C)
  • 资助金额：
    $2.25万
  • 财政年份：
    2014
  • 负责人：
    KOBAYASHI Kazuhiro
  • 依托单位：
    Tottori University
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  • 批准号：
    24300104
  • 项目类别：
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  • 资助金额：
    $11.56万
  • 财政年份：
    2012
  • 负责人：
    KOBAYASHI Kazuhiro
  • 依托单位：
    Kobe University
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  • 批准号：
    22550035
  • 项目类别：
    Grant-in-Aid for Scientific Research (C)
  • 资助金额：
    $2.41万
  • 财政年份：
    2010
  • 负责人：
    KOBAYASHI Kazuhiro
  • 依托单位：
    Tottori University
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