Effect of nocturnal exposure to short wavelength light on energy metabolism

晚间暴露在光线下，特别是短波长蓝光，会提高人的主观警觉性，抑制褪黑激素的分泌，并引起睡眠结构的变化。睡眠/清醒的控制与能量代谢的调节有关，夜间蓝光暴露可能也会影响睡眠中的能量代谢。本研究评估了夜间蓝光暴露对睡眠/觉醒控制和能量代谢的影响，直到次日中午。在平衡交叉设计中，9名受试者坐在房间大小的代谢室中，晚上暴露于蓝色LED(波长：465 nm，强度：12.1微W/cm2)或无光2小时。夜间暴露于低强度蓝光，不影响睡眠结构和睡眠中的新陈代谢，第二天早上会引起嗜睡和能量代谢抑制。

Evening light exposure,particularly, short wavelength blue light, increases subjective alertness, suppresses melatonin secretion and elicits changes in sleep architecture. Control of sleep/wakefulness is associated with the regulation of energy metabolism, it is plausible that evening blue light exposure might also affect energy metabolism during sleep. The present study assessed the effect of nocturnal blue light exposure on the control of sleep/wakefulness and energy metabolism until next noon. In a balanced cross-over design, 9 subjects sitting in a room-size metabolic chamber were exposed either to blue LED (wave length: 465 nm, intensity: 12.1 microW/cm2) or to no light for 2 h in the evening.Exposure to low intensity blue light in the evening, which did not affect sleep architecture and metabolism during sleep, elicited drowsiness and suppression of energy metabolism in the following morning.