Effect of nocturnal exposure to short wavelength light on energy metabolism

晚间暴露于光线，特别是短波长蓝光，会增加主观警觉性，抑制褪黑激素分泌并引起睡眠结构的变化。睡眠/觉醒的控制与能量代谢的调节有关，晚间蓝光暴露也可能影响睡眠期间的能量代谢。本研究评估了夜间蓝光暴露对睡眠/觉醒和能量代谢控制的影响，直到第二天中午。在一个平衡的交叉设计中，9名受试者坐在一个房间大小的代谢室中，（波长：465 nm，强度：12.1 microW/cm 2）或晚上无光2 h。晚上暴露于低强度蓝光（其不影响睡眠期间的睡眠结构和代谢）引起第二天早上的困倦和能量代谢抑制。

Evening light exposure,particularly, short wavelength blue light, increases subjective alertness, suppresses melatonin secretion and elicits changes in sleep architecture. Control of sleep/wakefulness is associated with the regulation of energy metabolism, it is plausible that evening blue light exposure might also affect energy metabolism during sleep. The present study assessed the effect of nocturnal blue light exposure on the control of sleep/wakefulness and energy metabolism until next noon. In a balanced cross-over design, 9 subjects sitting in a room-size metabolic chamber were exposed either to blue LED (wave length: 465 nm, intensity: 12.1 microW/cm2) or to no light for 2 h in the evening.Exposure to low intensity blue light in the evening, which did not affect sleep architecture and metabolism during sleep, elicited drowsiness and suppression of energy metabolism in the following morning.