Extraordinary Effect of Microwave Irradiation on Catalytic Organic Syntheses

本文报道了微波辐射对AgBF_4膦配合物催化的动力学拆分的联芳内酯对映体选择性开环反应的影响。采用带冷却系统的多模微波反应器，利用光纤传感器精确测量内反应温度。结果表明，在几乎与常规条件相同的内部温度下，微波辐射加速了反应的进行，且对映体选择性没有任何损失。根据Arrhenius对当前反应的作图，证实了微波效应不仅仅是它们的简单加热效应。

We here report the effect of microwave irradiation on the atropo-enantioselective ring-opening reaction of biaryl lactones with dynamickinetic resolution catalyzed by AgBF_4phosphine complexes. The multimode microwave reactor with a cooling system was employed and the fiber-optic sensor was used for measurement of the accurate internal reaction temperature. It was found that the reaction was accelerated by microwave irradiation without any loss of enantioselectivity at almost the same internal temperature as the conventional conditions. On the basis of Arrhenius plots on the present reaction, it was confirmed that the microwave effect was not only their simple heating effect.