Extraordinary Effect of Microwave Irradiation on Catalytic Organic Syntheses

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We here report the effect of microwave irradiation on the atropo-enantioselective ring-opening reaction of biaryl lactones with dynamickinetic resolution catalyzed by AgBF_4phosphine complexes. The multimode microwave reactor with a cooling system was employed and the fiber-optic sensor was used for measurement of the accurate internal reaction temperature. It was found that the reaction was accelerated by microwave irradiation without any loss of enantioselectivity at almost the same internal temperature as the conventional conditions. On the basis of Arrhenius plots on the present reaction, it was confirmed that the microwave effect was not only their simple heating effect.