Analysis of relations with cSrc and the radiation therapy in head and neck cancer patient
Analysis of relations with cSrc and the radiation therapy in head and neck cancer patient
头颈癌患者cSrc与放射治疗的关系分析
批准号：
23791939
负责人：
MATSUMOTO Fumihikoa
金额：
$2.66万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2011
资助国家：
日本
项目状态：
已结题
起止时间：
2011 至 2012
中文摘要
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英文摘要
The specimen was obtained by biopsy or surgery from patient was investigated by immunohistochemistry . The patients have high expression level of cSrc is more resistant to radiotherapy than low expression. Furthermore, the combination effect of anti IGF-1R and EGFR antibody and radiotherapy to head and neck cancer cell was examined in xenograft mouse model. The combination of anti-EGFR and IGF-1R and radiation showed high antitumor effect.
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会议论文
DOI：
10.1158/1078-0432.ccr-10-2120
发表时间：
2011-04-01
期刊：
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子：
--
作者：
[Sano D, Matsumoto F, Valdecanas DR, Zhao M, Molkentine DP, Takahashi Y, Hanna EY, Papadimitrakopoulou V, Heymach J, Milas L, Myers JN]
通讯作者：
Myers JN
DOI：
10.1007/s10637-009-9361-2
发表时间：
2011-06
期刊：
Investigational New Drugs
影响因子：
3.4
作者：
[O. Riesterer;F. Matsumoto;Li Wang;J. Pickett;D. Molkentine;U. Giri;L. Milas;U. Raju]
通讯作者：
O. Riesterer;F. Matsumoto;Li Wang;J. Pickett;D. Molkentine;U. Giri;L. Milas;U. Raju
The Impact of Timing of EGFR and IGF-1R Inhibition for Sensitizing
EGFR 和 IGF-1R 抑制时机对致敏的影响
EGFR 和 IGF-1R 抑制时机对致敏的影响
DOI：
--
发表时间：
2012
期刊：
Head and Neck Cancer to Radiation. Anticancer Res
影响因子：
--
作者：
[Matsumoto F, Valdecanas DN, Mason KA, Milas L, Ang KK, Raju U]
通讯作者：
Raju U
海外基金
