Strategic fusion of nuclear proteins dynamics of the malignant tumor and nuclear medicine

采用Western blot和组织细胞化学方法，观察了紫外线照射后SCC-25和HSG细胞核仁素和AgNORs蛋白的动态变化。核仁素和AgNORs蛋白的动态变化。 在核医学方面，根尖周或牙周炎引起的骨吸收面积与18F-FDG最高峰（SUVmax）的标准化摄取值之间存在显著相关性。18F-FDG的蓄积量可以准确反映炎症的程度。18F-FDG-PET阳性区域（不包括原发性肿瘤）包括舌前内肌（89.0%）、口轮匝肌上下缘部（64.6%）、舌下腺、腭扁桃体、咽扁桃体和舌扁桃体。此外，颌骨的一些区域也显示出蓄积。

Dynamic alteration of nucleolin and AgNORs proteins in UV-induced SCC-25 and HSG cells were examined using Western blot analysis and histocytochemistry methods. Dynamic alteration of nucleolin and AgNORs proteins are observed. With regard to nuclear medicine, A significant correlation was found between the size of bone resorption area by periapical or periodontal inflammation and standardized uptake value with the highest point (SUVmax) of 18F-FDG accumulations. 18F-FDG accumulations could exactly reflect the extent of the dental inflammation. 18F-FDG-PET-positive areas, excluding primary tumors, included the front intrinsic muscles of the tongue (89.0%), upper and lower marginal parts of the orbicularis oris muscle (64.6%), sublingual glands, palatine tonsil, pharyngeal tonsil, and lingual tonsil. In addition, some areas in the jaws also showed accumulation.