Prediction of lymph node metastasis from tongue carcinoma with diffusion-weighted MR imaging

在这项工作中，我们试图用体素内非相干运动（IVIM）分析来评估生物组织中的扩散和灌注，这是评估扩散加权MR成像的一种方法，使用幻影和健康志愿者。在幻象研究中，IVIM分析可以检测到送液流速的增加，这是灌注因子的变化。然而，在志愿者研究中获得的结果很差。除了这些研究外，本研究还评估了使用IVIM分析预测头颈部肿瘤的恶性程度，包括与表观扩散系数（ADC）的比较。使用IVIM分析可能有助于头颈部肿瘤的诊断。但其诊断能力不如ADC。结合使用IVIM参数和ADC有可能提高诊断能力。

In this work, we attempted to evaluate diffusion and perfusion in the biological tissues with intravoxel incoherent motion (IVIM) analysis, which was known as one method for assessing diffusion-weighted MR imaging, using phantom and healthy volunteers. In the phantom study, the increasing flow rate of solution sending could be detected as the change of perfusion factors in the IVIM analysis. However, poor results were obtained in the volunteer study. Aside from these studies, the use of IVIM analysis for predicting malignancy in the head and neck tumors including the comparison with apparent diffusion coefficient (ADC) was also evaluated in this work. The use of the IVIM analysis may be useful in the diagnosis of head and neck tumors. However, its diagnostic ability was inferior to ADC. The use of a combination of IVIM parameters and ADC has the potential to improve diagnostic ability.