Biomechanical analyses and preventing stress shielding of titaniumalloy's implant with a low Young's modulus.

点击翻译按钮获取中文摘要

Ti29Nb13Ta4.6Zr alloy (TNTZ) has excellent advantages as a biomaterial, such as low Young's modulus and cytotoxicity, and the absence of allergens. However, it is unclear whether TNTZ can achieve sufficient osseointegration to be used as a dental implant. The advantageous effect of surface modification of TNTZ implants by radiofrequency (RF) magnetron sputtering is also unclear. I investigated the biomechanical behaviors of TNTZ implants in vivo, using cylindrical implants of four types: pure Ti, TNTZ, and pure Ti and TNTZ coated with calcium phosphate (CaP). The implants were inserted in rat femurs, and the femurs were subjected to biomechanical analyses after various time intervals. The results suggest that TNTZ implants can achieve osseointegration similar to that of pure Ti, and that surface modification with CaP by RF magnetron sputtering improves osseointegration.