The characteristics of sleep habit and autonomic nerve activityat night in children with severe motor and intellectual disabilities .

为了解严重运动和智力障碍儿童夜间自主神经活动的特点，进行了一项调查。研究对象为18名符合Oshima分类1的儿童，平均年龄11.6(SD 3.0)岁，正常儿童平均年龄11.2(SD 3.7)岁。连续3天用Actiwatch 2测量睡眠开始时间、睡眠结束时间、睡眠潜伏期、睡眠时间和觉醒时间。用ActiHR4测量心率变异性(HRV)，时间为晚上8：00~早上8：00，连续3天。以心率变异性(HRV)从入睡开始到入睡结束时评价患者睡眠时的自主神经活动指标：低频(LF)、高频(HF)、低频/高频(LF/HF)。重度运动和智力障碍儿童的睡眠习惯与正常儿童相似。其中LF/HF显著高于正常儿童。我们认为，严重运动和智力残疾儿童的中枢神经功能障碍可能会影响心脏自主神经活动，并导致睡眠中的交感神经过度活动。

An investigation was carried out to determine the characteristics of autonomic nerve activity at night in children with severe motor and intellectual disabilities . Subjects were 18 children who matched Oshima‘s classification 1 with mean age of 11.6 (SD 3.0) years and normal children with mean age of 11.2 (SD 3.7) years. Actiwatch2 was used to measure sleep start, sleep end, sleep latency, sleep time and awaking time for three consecutive days. ActiHR4 was used to measure heart rate variability (HRV) from 8:00pm to 8:00am for three consecutive days. The indexes of autonomic nerve activity; low frequency (LF), high frequency (HF), LF/HF, during sleep time was evaluated by HRV from sleep start to end time. Sleep habit of children with severe motor and intellectual disabilities was similar to normal children. LF/HF of them was significantly higher than normal children. We believe the central neural dysfunction of children with severe motor and intellectual disabilities may affect the cardiac autonomic nervous activity and cause sympathetic hyperactivity during sleep.