Development of novel fiber-based light sources for coherent Raman scattering imaging

本研究的重点是发展新型光纤光源，用于相干拉曼散射显微镜中快速稳定的光谱成像。利用高非线性光纤将零色散波长调谐到近红外波段，研制了一种光学参量振荡器和稳定的超连续谱光源。建立了相干反斯托克斯拉曼散射（汽车）显微镜和近场汽车显微镜的光源，开发。汽车光谱的DNA组成分子的指纹区域进行测量，而不修改的泵和斯托克斯脉冲之间的群延迟，显着减少数据采集时间。此外，对于孤立的单壁碳纳米管实现了高分辨率汽车成像，空间分辨率为60 nm，光谱分辨率为30 cm-2<-1>。这些结果发表在科学文献中。

This research focused on the development of novel fiber sources for rapid and stable spectral imaging in a coherent Raman scattering microscope. An optical parametric oscillator as well as a stable supercontinuum source were developed using a highly nonlinear optical fibers with their zero dispersion wavelengths tuned to near-infrared wavelengths. Having established the light sources, a coherent anti-Stokes Raman scattering (CARS) microscope and a near-field CARS microscope were developed. CARS spectra of DNA constituent molecules in the finger-print region were measured without modifying the group delay between the pump and the Stokes pulses, significantly decreasing the data acquisition time. Moreover, high resolution CARS imaging was realized for an isolated single-walled carbon nanotube with spatial resolution of 60 nm and spectral resolution of 30 cm^<-1>. These results were published in a scientific literature.