Development of novel fiber-based light sources for coherent Raman scattering imaging

本研究致力于开发用于相干拉曼散射显微镜中快速稳定的光谱成像的新型光纤光源。利用零色散波长调谐到近红外波长的高度非线性光纤，研制了光学参量振荡器和稳定的超连续谱光源。在确定光源的基础上，研制了相干反斯托克斯拉曼散射(CARS)显微镜和近场CARS显微镜。在不改变泵浦和斯托克斯脉冲之间的群延迟的情况下，测量了指纹区DNA组成分子的CARS光谱，显著减少了数据采集时间。此外，还实现了空间分辨率为60 nm、光谱分辨率为30 cm^&lt；-1的孤立单壁碳纳米管的高分辨率CARS成像。这些结果发表在一篇科学文献上。

This research focused on the development of novel fiber sources for rapid and stable spectral imaging in a coherent Raman scattering microscope. An optical parametric oscillator as well as a stable supercontinuum source were developed using a highly nonlinear optical fibers with their zero dispersion wavelengths tuned to near-infrared wavelengths. Having established the light sources, a coherent anti-Stokes Raman scattering (CARS) microscope and a near-field CARS microscope were developed. CARS spectra of DNA constituent molecules in the finger-print region were measured without modifying the group delay between the pump and the Stokes pulses, significantly decreasing the data acquisition time. Moreover, high resolution CARS imaging was realized for an isolated single-walled carbon nanotube with spatial resolution of 60 nm and spectral resolution of 30 cm^<-1>. These results were published in a scientific literature.