Spatial regulation mechanism of initiation of meiotic recombination

减数分裂是有性生殖的一种特殊类型的细胞分裂，产生配子。同源染色体之间的基因重组是减数分裂所必需的。重组中的缺陷导致生物多样性下降和染色体异常引起的疾病。减数分裂染色体与各种蛋白质相互作用。这种相互作用动态地改变了染色体结构。在这项研究中，我们利用全基因组分析和生物信息学分析了染色体结构蛋白减数分裂重组的启动机制。

Meiosis is a special type of cell division for sexual reproduction and produces gametes.Genetic recombination between homologous chromosomes is required for meiosis. A defect in the recombination results in declining biodiversity and disorders caused by chromosomal abnormality. Meiotic chromosomes interact with various proteins. Theinteraction dynamically alters chromosome structure. In this study, we analyzed an initiation mechanism of meiotic recombination by a chromosomal structural protein using genome-wide analyses and bioinformatics.