Identificationand clinical application of genetic markers for effectivedrug therapy of psychiatric disorders.

有人认为，对主要抑郁症的易感性和抗抑郁药的反应性是遗传特征，但受多种因素的复杂组合影响。对影响这些特征的遗传因素的综合研究可能会为患者带来有利的个体化治疗。本研究使用抑郁症患者和健康志愿者的样本，研究了遗传因素与抑郁症易感性和/或抗抑郁药物反应之间的关系，所得数据可能有助于进一步的研究。

It has been suggested that susceptibility tomajor depression and responsestoantidepressants are genetically inherited traits, but are subjectto a complex combination of factors. Comprehensiveinvestigations ofgenetic factors that influence these traits may lead tofavorableindividualized treatmentsfor patients. In this study, the association between genetic factors and susceptibility tomajor depression and/orresponsestoantidepressants was investigated using samples from patientswith depression and healthy volunteers.The resulting datamay be helpful infurther investigations.