Effect of imatinib in bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation
Effect of imatinib in bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation
批准号:
23790901
负责人:
WASEDA Yuko
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
在小鼠肺移植模型中,当我们使用c-kit敲除模型作为供体时,BO被显著控制。我们有可能通过控制供体的c-kit来减少BO,这是肺移植后最大的并发症。因此,我们考虑用伊马替尼减少BO的可能性。
英文摘要
In the mouse lung transplantation model, BO was significantly controlled when we used the c-kit knockout model as donor. We had the possibility to be able to reduce BO, which is the biggest complications after the lung transplantation, by controlling c-kit of the donor. Therefore, We thought about the possibility that we could decrease BO with imatinib.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The role of c-Kit in mice model of heterotopic tracheal transplantation
-
批准号:25860639
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2013
-
负责人:WASEDA Yuko
-
依托单位:
海外基金