Immunotherapy utilizing dendritic cells derived from iPS cells
Immunotherapy utilizing dendritic cells derived from iPS cells
批准号:
23791280
负责人:
FUKUSHIMA Satoshi
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
We establish a streamlined process to generate the dendritic cells from mouse iPS cells and ES cells. To enhance the anti-tumor effect, we generated a ES cell clone expressing IL-15. Furthermore, we generated the macrophages derived from human iPS cells as an effector cells attacking tumor . The iPS cell derived macrophages itself did not show any anti-tumor effects on human melanoma grafted SCID mouse model. However ,genetically modified cytokine producing iPS macrophages show a potent anti tumor effects.
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DOI:
10.1159/000341111
发表时间:
2012-05
期刊:
Case reports in dermatology
影响因子:
0.9
作者:
[Oshikawa Y, Fukushima S, Miyake T, Kawaguchi T, Motomura K, Nakashima Y, Nakamura K, Jinnin M, Ihn H]
通讯作者:
Ihn H
Case of blastic plasmacytoid dendritic cell neoplasm.
母细胞性浆细胞样树突状细胞肿瘤病例。
DOI:
10.1111/j.1346-8138.2012.01656.x
发表时间:
2012
期刊:
J Dermatol.
影响因子:
--
作者:
[Kudo H, Jinnin M, Yamane K, et al, Aoi J]
通讯作者:
Aoi J
メラノーマに対する化学療法 upto date
黑色素瘤化疗最新进展
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Honda N, Jinnin M, Kajihara I, Makino T, Makino K, Masuguchi S, Fukushima S, Okamoto Y, Hasegawa M, Fujimoto M, Ihn H., 福島聡]
通讯作者:
福島聡
メラノーマの免疫療法とバイオマーカー
黑色素瘤免疫疗法和生物标志物
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Ichihara A, Jinnin M, Oyama R, Yamane K, Fujisawa A, Sakai K, Masuguchi S, Fukushima S, Maruo K, Ihn H., 福島聡]
通讯作者:
福島聡
DOI:
--
发表时间:
2013
期刊:
Clinical and experimental rheumatology
影响因子:
3.7
作者:
[S. Shimada;M. Jinnin;A. Ogata;T. Makino;I. Kajihara;K. Makino;N. Honda;Wakana Nakayama;Kuniko Inoue;S. Fukushima;H. Ihn]
通讯作者:
S. Shimada;M. Jinnin;A. Ogata;T. Makino;I. Kajihara;K. Makino;N. Honda;Wakana Nakayama;Kuniko Inoue;S. Fukushima;H. Ihn
共 32 条
Immunotherapy with genetically modified iPS cell-derived macrophages against melenoma
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批准号:25870545
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.83万
-
财政年份:2013
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负责人:FUKUSHIMA Satoshi
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依托单位:
Critical path analysis of early education program for hearing impaired children
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批准号:24243080
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$20.8万
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财政年份:2012
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负责人:FUKUSHIMA Satoshi
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依托单位:
The development of novel cancer-immunotherapy utilizing dendritic cells derived from iPS cells.
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批准号:21890199
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项目类别:Grant-in-Aid for Research Activity Start-up
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资助金额:$1.66万
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财政年份:2009
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负责人:FUKUSHIMA Satoshi
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依托单位:
The Practical Study of the Real-time Captioning System Using Automatic Speech Recognition Technology in order to Support Students with Hearing Impairment
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批准号:16530617
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:FUKUSHIMA Satoshi
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依托单位:
海外基金