Functional brain imaging and the longitudinal changes of depressive states in major psychiatric disorders

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The main strengths of the study include the application of a neuroimaging biomarker in clinical practice that allows the clinically useful differential diagnosis, the assessment of symptoms, and the prognostic predictions. Some of our studies provided evidence that the fronto-temporal NIRS signal may be used as a tool in assisting the diagnosis of major psychiatric disorders and the assessment of symptoms. The current studies have shown the potential applicability of this method to the identification of a need for therapy, the assessment of the efficacy of various treatments, and the establishment of prognostic predictions. The availability of such a comprehensively visualized report to clinicians, patients and their caretakers at a first visit, while laying out a future treatment plan, would likely lead to a paradigm shift to a patient-centered approach in clinical psychiatry.