マウス内耳発生～ステレオシリアの形成～におけるＳｕｌｆ１の役割の解明

阐明 Sulf1 在小鼠内耳发育中的作用 - 静纤毛的形成

• 批准号: 12F02211
• 负责人: RAJ Ladher (2013-2014)
• 金额: $ 1.54万
• 依托单位: The Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for JSPS Fellows
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012 至 2014
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12F02211/
• 关键词: ステレオシリア; 内耳発生; Inner ear; Sulfatase; FGF; hair cell

Since April 2014 Dr. Freeman has been preparing two manuscripts for submission to academic journals. His original deadline for submission of these papers was May 31st, 2014. However, he extended this deadline in order to collect additional data that will increase the impact and solidity of his results. He has now completed the collection of this additional data and has finished writing his primary manuscript. The final draft of this manuscript has been completed and is currently being checked by Dr Raj Ladher and Dr Masayuki Masu to ensure it is acceptable for submission. Dr. Freeman will submit the manuscript to the Developmental Dynamics journal, within the "Patterns and Phenotypes" section. Dr. Freeman has also been preparing another manuscript in collaboration with researchers working in Dr Alain Dabdoub's laboratory at The University of Toronto, Canada. This manuscript was submitted to the Biology of the Cell journal in June 2014, and in response to the reviewers comments he has been collecting additional data and incorporating this into the manuscript. The manuscript will be resubmitted to Biology of the Cell at the end of August 2014.Finally Dr. Freeman has been collecting some preliminary data to allow him to build upon the research he has performed during his JSPS fellowship during the next phase of his career as a research scientist.

自2014年4月以来，Freeman博士一直在准备两篇论文提交给学术期刊。他最初提交这些论文的截止日期是2014年5月31日。然而，他延长了这一期限，以便收集更多的数据，增加其结果的影响力和可靠性。他现在已经完成了这些额外数据的收集，并完成了他的主要手稿。这份手稿的最终草案已经完成，目前正在由Raj Ladher博士和Masayuki Masu博士进行检查，以确保可以提交。弗里曼博士将把手稿提交给《发育动力学》杂志的“模式和表型”部分。Freeman博士还与加拿大多伦多大学Alain Dabdoub博士实验室的研究人员合作准备了另一份手稿。这份手稿于2014年6月提交给了《细胞生物学》杂志，为了回应审稿人的评论，他一直在收集更多的数据并将其纳入手稿。该手稿将于2014年8月底重新提交给细胞生物学。最后，Freeman博士一直在收集一些初步数据，以便在他作为研究科学家的职业生涯的下一阶段，在他的JSPS奖学金期间进行的研究的基础上进行研究。