Vascularized tumour models to elucidate the delivery of nanomedicine agents

血管化肿瘤模型阐明纳米药物的输送

• 批准号: DE150100564
• 负责人: Dr Chia-Chi Chien
• 金额: $ 27.6万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE150100564
• 关键词: Vascularized; tumour; models; elucidate; delivery

This inter-disciplinary project aims to develop advances in in vitro models aimed at elucidating the delivery and transport of diagnostic and therapeutic nanomedicine agents in tumour tissues. The project aims to build on advanced tissue engineering principles and state-of-the-art micro-fabrication technologies to remove the limitation associated with animal studies and provide unprecedented mechanistic insights into the delivery, transport and binding of nanomedicines into tumour tissues.

该跨学科项目旨在开发体外模型的进展，旨在阐明诊断和治疗纳米药物在肿瘤组织中的传递和运输。该项目旨在建立在先进的组织工程原理和最先进的微制造技术的基础上，以消除与动物研究相关的限制，并为纳米药物进入肿瘤组织的递送、运输和结合提供前所未有的机械见解。