Detection system for the influenza virus by novel functional polymer and artificial enzyme

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The hemagglutinin protein on influenza virus can recognize the sialic acid on the cell membrane, and the virus infects the human cell. In this study, we utilize this mechanism to prepare the functional membrane, which can detects the influenza virus. This functional membrane was prepared by radiation-induced graft polymerization. To immobilize the sialic acid as the recognition site of the hemagglutinin protein on the influenza virus, the coupled iminodiacetic acid and 1-ethyl-3-carbodiimide hydrochloride was introduced onto the porous hollow fiber membrane. Copper ion as a signal substance was adsorbed on the sialic acid immobilizesd porous hollow fiber membrane, and it indicated the possibility of the sensor for influenza virus.