Detection of oxidized ERprotein by nitrosative/oxidative stress with a specific antibody
Detection of oxidized ERprotein by nitrosative/oxidative stress with a specific antibody
批准号:
23659041
负责人:
UEHARA Takashi
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The aim of this study is to establish the assay system to detect oxidized PDI (PDI-SO3H) with a specific antibody. We succeeded to isolate several specific antibodies against PDI-SO3H. An antibody could detect the oxidized form of PDI treated with H2O2, NO, or rotenone. This antibody might be useful for diagnosis of sporadic neurodegenerative disprders such as Alzheimer’s and Parkinson’s diseases.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Detection of oxidized protein-disulfide isomerase with a specific antibody
用特异性抗体检测氧化蛋白二硫键异构酶
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Uehara, T., 上原孝, 西屋禎, 改田祐子, Takashi Uehara]
通讯作者:
Takashi Uehara
Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody
使用特异性抗体检测亚硝化/氧化应激引起的氧化 ER 蛋白
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Uehara, T.]
通讯作者:
T.
岡山大学大学院医歯薬学総合研究科薬効解析学分野
冈山大学生物医学科学研究生院药效分析系
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
脳21
大脑 21
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[岡本秀彦, 武田憲昭, 日比野浩, 任書晃, 倉智嘉久, 森望, 宮下武憲, 稲本隆平, 松原あい, 星川広史, 松永達雄, 大島一男, 土井勝美, 西池季隆, 北原糺, 今井貴夫, 佐藤豪, 堀井新, 佐藤崇, 肥塚泉, 宇野敦彦, 大崎康宏, 東貴弘, 石川保幸, 山岸覚, 鈴木育浩, 前田光代, 田口明彦, 臼井紀好, 馬場明道, 村山繁雄]
通讯作者:
村山繁雄
発癌/神経細胞の生死に関わる細胞内ROSシグナル制御,細胞工学
癌变/神经细胞生死相关的细胞内ROS信号控制、细胞工程
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Ichijo, H., 鎌田英明,上原 孝]
通讯作者:
鎌田英明,上原 孝
共 32 条
Effect of omega-3 supplementation on behavioral and psychological symptoms of dementia
-
批准号:17K10319
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2017
-
负责人:UEHARA Takashi
-
依托单位:
Identification of novel target proteins of NO with new screening system
-
批准号:25670029
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2013
-
负责人:UEHARA Takashi
-
依托单位:
Effects of metformin in combination with chemotherapeutic agents on endometrial carcinoma cells
-
批准号:24791686
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2012
-
负责人:UEHARA Takashi
-
依托单位:
Molecular mechanism of neuronal cell death induced by methyl mercury via endoplasmic reticulum stress
-
批准号:22310039
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.56万
-
财政年份:2010
-
负责人:UEHARA Takashi
-
依托单位:
Pathophysiological function of nitric oxide on protein quality control system in endoplasmic reticulum.
-
批准号:19590051
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2006
-
负责人:UEHARA Takashi
-
依托单位:
Essential polyunsaturated fatty acids and neuropsychiatric symptoms in Alzheimer's disease
-
批准号:18591276
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.46万
-
财政年份:2006
-
负责人:UEHARA Takashi
-
依托单位:
Possible relationship between S-nitrosylated proteins and neurodegenerative disorders
-
批准号:17590050
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2005
-
负责人:UEHARA Takashi
-
依托单位:
海外基金