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Molecular mechanism of metabolic regulation by TRPM7

Molecular mechanism of metabolic regulation by TRPM7
TRPM7代谢调节的分子机制
批准号:
23659114
负责人:
MATSUSHITA Masayuki
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
We have made the kinase dead knock-in mouse with replacement of the key residue for ATP binding in kinase domain to investigate a possible role of kinase activity f TRPM7. This mutant mouse grows normally, but show significant abnormality of cholesterol metabolism. In addition, we identified the cholesterol secretion from hepatocyte was severely defect in these mutant mouse.
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会议论文
Sensitivity of TRPM7 channels...
TRPM7 通道的灵敏度...
DOI: --
发表时间: 2012
期刊: Am J Physiol Cell Physiol
影响因子: --
作者: [Chokshi R, Matsushita M, Kozak JA.]
通讯作者: Kozak JA.
キナーゼ活性を持つTRPM7 チャネルの機能解析
TRPM7通道与激酶活性的功能分析
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Masato Koike, Yasuo Uchiyama, 松下正之]
通讯作者: 松下正之
Pathogenesis of schizophrenia using neural induction system from iPS Cell
  • 批准号:
    15K15033
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.33万
  • 财政年份:
    2015
  • 负责人:
    MATSUSHITA Masayuki
  • 依托单位:
The strategy for treatment neuronal diseases using cell specific CPPs
  • 批准号:
    25293048
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $10.98万
  • 财政年份:
    2013
  • 负责人:
    MATSUSHITA Masayuki
  • 依托单位:
Strategy for treatment of diseases by cell type specific invasive peptides
  • 批准号:
    22390038
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $11.73万
  • 财政年份:
    2010
  • 负责人:
    MATSUSHITA Masayuki
  • 依托单位:
Regulation and Analysis of Excitatory Neuronal Cell Death by Protein Transduction Therapy
  • 批准号:
    17500212
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.18万
  • 财政年份:
    2005
  • 负责人:
    MATSUSHITA Masayuki
  • 依托单位:
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