Epidemiological analysis and risk analysis of enterovirus C in the Philippines

菲律宾丙型肠道病毒流行病学分析及风险分析

• 批准号: 23659343
• 负责人: OSHITANI Hitoshi
• 金额: $ 2.41万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659343/
• 关键词: エンテロウイルス; ポリオウイルス; フィリピン; ポリオ根絶計画; ワクチン株由来ポリオウイルス

Human enteroviruses (HEV) are classified into four species (HEV-A, B, C, and D). Epidemiology of HEV-C is still widely unknown. We typed non-polio enteroviruses, which had been isolated from acute flaccid paralysis cases during 17 years of polio surveillance in the Philippines. As results, 108 strains among a total of 790 non-polio enteroviruses were typed as HEV-C. Also one of HEV-C identified in this study was shown to be closely related to the virus detected in paralysis cases in 2001. Furthermore, HEV-C was detected from river water samples collected in urban and ruralareas in the Philippines.

人类肠道病毒 (HEV) 分为四种（HEV-A、B、C 和 D）。 HEV-C 的流行病学仍广为人知。我们对非脊髓灰质炎肠道病毒进行了分型，这种病毒是在菲律宾 17 年脊髓灰质炎监测期间从急性弛缓性麻痹病例中分离出来的。结果，总共790种非脊髓灰质炎肠道病毒中有108株被定型为HEV-C。此外，本研究中发现的一种HEV-C与2001年瘫痪病例中检测到的病毒密切相关。此外，从菲律宾城市和农村地区收集的河水样本中也检测到了HEV-C。

项目成果

Characterization of Coxsackievirus A20 as the donor strain of the recombinant type 1 circulating vaccine-derived polioviruses in the Philippines

菲律宾柯萨奇病毒 A20 作为重组 1 型疫苗衍生脊髓灰质炎病毒供体株的特征

• 发表时间: 2012
• 作者: Okada C;Matsuo H;Apostol LN
• 通讯作者: Apostol LN

Identification of Coxsackievirus A20...

柯萨奇病毒 A20 的鉴定...

• 发表时间: 2012
• 作者: 林節男;寺西秀豊;Apostol LN;寺西秀豊,福島千鶴子,鏑木望未,吉田行夫;岸玲子;Lea Necitas APOSTOL
• 通讯作者: Lea Necitas APOSTOL

Genetic diversity and molecular characterization of enteroviruses from sewage-polluted urban and rural rivers in the Philippines.

• DOI: 10.1007/s11262-012-0776-z
• 发表时间: 2012-10
• 期刊: VIRUS GENES
• 影响因子: 1.6
• 作者: Apostol, Lea Necitas G.;Imagawa, Tomifumi;Suzuki, Akira;Masago, Yoshifumi;Lupisan, Socorro;Olveda, Remigio;Saito, Mariko;Omura, Tatsuo;Oshitani, Hitoshi
• 通讯作者: Oshitani, Hitoshi

Detection of nonpolio enteroviruses from...

检测非脊髓灰质炎肠道病毒...

• 发表时间: 2012
• 期刊: Jouｒnal Medical Virology
• 作者: Lea Necitas APOSTOL...;Hitoshi OSHITANI
• 通讯作者: Hitoshi OSHITANI

Detection of non-polio enteroviruses from 17 years of virological surveillance of acute flaccid paralysis in the Philippines.

• DOI: 10.1002/jmv.23242
• 发表时间: 2012-04
• 期刊: JOURNAL OF MEDICAL VIROLOGY
• 影响因子: 12.7
• 作者: Apostol, Lea Necitas;Suzuki, Akira;Bautista, Analisa;Galang, Hazel;Paladin, Fem Julia;Fuji, Naoko;Lupisan, Socorro;Olveda, Remigio;Oshitani, Hitoshi
• 通讯作者: Oshitani, Hitoshi