课题基金 / 基金详情

capsaiate CH-19 sweet is possible to prevent aspiration pneumonia in the elderly

capsaiate CH-19 sweet is possible to prevent aspiration pneumonia in the elderly
辣椒酸CH-19甜可预防老年人吸入性肺炎
批准号:
23659375
负责人:
EBIHARA TAKAE
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

项目摘要

项目成果

EBIHARA TAKAE的其他基金

相关文献

中文摘要
翻译
Capsiate是由'CH-19 Sweet'生产的,这是一种非辛辣的红辣椒品种。像辣椒素一样,辣椒素被认为通过激活交感神经系统和抑制炎症来增强能量代谢。此外,我们以前报道瞬时受体电位香草酸1(TRPV 1)激动剂可以改善吞咽反射,这是老年人肺炎微吸入的危险因素之一。然而,TRP激动剂(包括辣椒素和辣椒素)是否对吞咽有影响尚不清楚。通过视频荧光检查,对吞咽困难导致的营养不良水平的参与者进行吞咽功能检查。结果表明,服用胶囊帽的人,其张开或闭合时间、各部位扩张程度及发育期均明显改善(P<0.01)。Capsiate(CH-19 sweet)能改善吞咽的感觉和运动反射。
英文摘要
Capsiate is produced by'CH-19 Sweet',a non-pungent cultivar of red pepper. Like capsaicin, capsiate is thought to enhance energy metabolism by activating the sympathetic nervous system and suppressing inflammation. In addition, we previously reported that transient receptor potential vanilloid 1(TRPV1) agonist can improve the swallowing reflex, which is one of risk factor of microaspiration for penumonia in the elderly. However, it is unknown whether TRP agonist including capsaicin and capsiate exert on the bolus swallows.Participants at the level of malnutrition by dysphagia were examined their function of swallowing by videofluorography.They were given capsaite-topped jelly or capsiate-untopped jelly. This result have shown that the opening or closure time, the degree of expansion of various parts oropharungeal stage people given capsiate-topped jerry was significantly improved(P<0.01). Capsiate(CH-19 sweet)can improve the sensory and motor reflex of swallowing.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Dysphagia in dementia
痴呆症吞咽困难
DOI: --
发表时间: 2011
期刊: Nihon Rinsho
影响因子: --
作者: [Kanezaki M, Ebihara S, Gui P, Ebihara T, Kohzuki M., Katayama K,Chun-Yan Liu,Mu-Qun Xia,et al., Ebihara S and Ebihara T]
通讯作者: Ebihara S and Ebihara T
DOI: 10.1016/j.rmed.2011.12.007
发表时间: 2012-03-01
期刊: RESPIRATORY MEDICINE
影响因子: 4.3
作者: [Kanezaki, Masashi, Ebihara, Satoru, Kohzuki, Masahiro]
通讯作者: Kohzuki, Masahiro
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Hibi S, Yamaguchi Y, Umeda-Kameyama Y, Takahashi M, Momose T, Akishita M, Ouchi Y., 海老原 孝枝]
通讯作者: 海老原 孝枝
DOI: 10.1254/jphs.10r05cp
发表时间: 2011-02-01
期刊: JOURNAL OF PHARMACOLOGICAL SCIENCES
影响因子: 3.5
作者: [Ebihara, Satoru, Kohzuki, Masahiro, Ebihara, Takae]
通讯作者: Ebihara, Takae
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