Molecular mechanism of urticarial development
Molecular mechanism of urticarial development
批准号:
23659550
负责人:
HIRAKAWA Satoshi
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
The biochemical cleavage of VE-cadherin was found in cultured endothelial cells. Western blot analysis from cell lysates and conditioned media revealed that VE-cadherin undergoes ectodomain shedding in response to histamine, leading to the disruption of EC junctions and the induction of vascular hyperpermeability. These findings represent the development of urticaria, a pathological alteration of vasculature in the skin.
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DOI:
10.1016/j.jdermsci.2010.09.008
发表时间:
2010-12-01
期刊:
JOURNAL OF DERMATOLOGICAL SCIENCE
影响因子:
4.6
作者:
[Dai, Xiuju, Sayama, Koji, Hashimoto, Koji]
通讯作者:
Hashimoto, Koji
Multiple milia and comedones as a skin manifestation of systemic amyloidosis.
多发性粟丘疹和粉刺是系统性淀粉样变性的皮肤表现。
DOI:
--
发表时间:
2011
期刊:
European Journal of Dermatology
影响因子:
2.5
作者:
[Funai N, Machida S, Ito T, Hirakawa S, Tokura Y.]
通讯作者:
Tokura Y.
特許
专利
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1371/journal.pone.0011275
发表时间:
2010-06-23
期刊:
PloS one
影响因子:
3.7
作者:
[Sayama K, Kajiya K, Sugawara K, Sato S, Hirakawa S, Shirakata Y, Hanakawa Y, Dai X, Ishimatsu-Tsuji Y, Metzger D, Chambon P, Akira S, Paus R, Kishimoto J, Hashimoto K]
通讯作者:
Hashimoto K
皮膚と循環:血管・リンパ管から考える病態生理
皮肤与循环:血管和淋巴管角度的病理生理学
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Sayama K, Kajiya K, Sugawara K, Sato S, Hirakawa S, Shirakata Y, Hanakawa Y, Dai X, Ishimatsu-Tsuji Y, Metzger D, Chambon P, Akira S, Paus R, Kishimoto J, Hashimoto K, 平川 聡史, 平川 聡史, 平川聡史]
通讯作者:
平川聡史
共 34 条
Biological effect of VEGF-C on cultured lymphatic endothelial cells
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批准号:25670501
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2013
-
负责人:HIRAKAWA Satoshi
-
依托单位:
Biochemical process of membrane-associated protein is induced by inflammatory cytokines in cultured lymphatic endothelial cells
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批准号:23390283
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.48万
-
财政年份:2011
-
负责人:HIRAKAWA Satoshi
-
依托单位:
Induction of lymphangiogenesis by membrane-binding growth factors
-
批准号:20591348
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2008
-
负责人:HIRAKAWA Satoshi
-
依托单位:
Molecular mechanisms of lymphangiogenesis in cutaneous neoplasms
-
批准号:20013032
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
-
资助金额:$11.52万
-
财政年份:2008
-
负责人:HIRAKAWA Satoshi
-
依托单位:
海外基金