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Induction of lymphangiogenesis by membrane-binding growth factors

Induction of lymphangiogenesis by membrane-binding growth factors
膜结合生长因子诱导淋巴管生成
批准号:
20591348
负责人:
HIRAKAWA Satoshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
The present study demonstrated that type I transmembrane proteins undergo ectodomain shedding in cultured human lymphatic endothelial cells. ADAM17 or ADAM10 is responsible for shedding via the activation of MAP kinase pathway. These results indicate that lymphangiogensis is mediated by the biochemical process of membrane-binding proteins.
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DOI: 10.2353/ajpath.2009.090420
发表时间: 2009-11-01
期刊: AMERICAN JOURNAL OF PATHOLOGY
影响因子: 6
作者: [Hirakawa, Satoshi, Detmar, Michael, Hashimoto, Koji]
通讯作者: Hashimoto, Koji
DOI: 10.1242/jcs.031443
发表时间: 2008-11-01
期刊: JOURNAL OF CELL SCIENCE
影响因子: 4
作者: [Isokane, Mayumi, Hieda, Miki, Higashiyama, Shigeki]
通讯作者: Higashiyama, Shigeki
DOI: 10.1371/journal.pone.0011275
发表时间: 2010-06-23
期刊: PloS one
影响因子: 3.7
作者: [Sayama K, Kajiya K, Sugawara K, Sato S, Hirakawa S, Shirakata Y, Hanakawa Y, Dai X, Ishimatsu-Tsuji Y, Metzger D, Chambon P, Akira S, Paus R, Kishimoto J, Hashimoto K]
通讯作者: Hashimoto K
Possible association of vascular endothelial growth factor with the development of edema in drug-induced hypersensitivity syndrome.
血管内皮生长因子与药物引起的超敏反应综合征中水肿的发生可能存在关联。
DOI: --
发表时间: 2011
期刊: J Dermatol. 38
影响因子: --
作者: [Hirakawa S, Okazaki H, Sayama K, Tohyama M, Hashimoto K.]
通讯作者: Hashimoto K.
26
    Biological effect of VEGF-C on cultured lymphatic endothelial cells
    • 批准号:
      25670501
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2013
    • 负责人:
      HIRAKAWA Satoshi
    • 依托单位:
    Molecular mechanism of urticarial development
    • 批准号:
      23659550
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2011
    • 负责人:
      HIRAKAWA Satoshi
    • 依托单位:
    Biochemical process of membrane-associated protein is induced by inflammatory cytokines in cultured lymphatic endothelial cells
    • 批准号:
      23390283
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.48万
    • 财政年份:
      2011
    • 负责人:
      HIRAKAWA Satoshi
    • 依托单位:
    Molecular mechanisms of lymphangiogenesis in cutaneous neoplasms
    • 批准号:
      20013032
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $11.52万
    • 财政年份:
      2008
    • 负责人:
      HIRAKAWA Satoshi
    • 依托单位:
    海外基金