Establishments of in vivo imaging technique for functional visualization ofadipose tissue and its potential application for diagnosis.

我们的研究不仅关注脂肪组织重量和脂肪细胞大小增加的形态学变化，还关注脂肪组织基因表达和代谢的功能变化。在本报告中，我们试图建立一种体内成像技术，使用脂肪因子报告基因作为脂肪功能变化的指标。在未来，使用这种成像技术，我们可以为增加的脂肪组织的病理生理方面提供有用的诊断指标

Our studies focused not only on morphological changes in an increase of adipose-tissue weight and adipocyte size, but also on functional changes in gene expression and metabolism of adipose tissue. In this report, we tried to establish an in vivoimaging technique using an adipokine-reporter gene as indicator of adipose-functional changes. In the future, using this imaging technique, we may provide a useful index of diagnosis for patho-physiological aspects of increased adipose tissue