The study of application of microRNA to radiation therapy

microRNA在放射治疗中的应用研究

• 批准号: 23659603
• 负责人: ZENDA Sadamoto
• 金额: $ 2.33万
• 依托单位: National Cancer Center Japan
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659603/
• 关键词: microRNA; miRNA; 放射線感受性; アポトーシス

MicroRNA is the cellular RNA which was identified controlling expression of protein at a translation level in late years. There are many unknown parts about the function. However, some microRNAs about radiosensitivity of the cell are reported, and it is thought that new knowledge about the biological influence of the radiation may be provided if relations with microRNA and the radiosensitivity are analyzed in detail. It was thought that some microRNAs concerned radiosensitivity from the result of this study.

MicroRNA是近年来发现的在翻译水平上控制蛋白质表达的细胞RNA。关于这个函数，还有很多未知的部分。然而，一些关于细胞辐射敏感性的microRNA已有报道，如果详细分析与microRNA和辐射敏感性的关系，可能会对辐射的生物学影响提供新的知识。根据本研究的结果，认为一些microRNAs与辐射敏感性有关。

项目成果

Proton Beam Therapy for Patients with Malignancies of The Nasal Cavity, Para-nasal Sinuses, and/or Involving The Skull base : The Analysis of Late Toxicity

鼻腔、鼻旁窦和/或颅底恶性肿瘤患者的质子束治疗：晚期毒性分析

• 发表时间: 2011
• 作者: Rie Saitoh;Kosuke Tsuji;Ryota Yamazaki;Hiroshi Hyodo;Kohei Soga;Hidehiro Kishimoto;Izumi O. Umeda;Hirofumi Fujii;Sadamoto Zenda
• 通讯作者: Sadamoto Zenda

ワークショップ頭頸部癌治療-最新の知見―

头颈癌治疗研讨会 - 最新知识 -

• 发表时间: 2011
• 作者: Sadaaki Kimura;Takuya Kuriyama;Yoshiki Kojima;Izumi O. Umeda;Noriyuki Moriyama;Hirofumi Fujii;櫻庭 均;全田貞幹
• 通讯作者: 全田貞幹

Multicenter phase II study of an opioid-based pain control program for head and neck cancer patients receiving chemoradiotherapy

• DOI: 10.1016/j.radonc.2011.09.016
• 发表时间: 2011-12-01
• 期刊: RADIOTHERAPY AND ONCOLOGY
• 影响因子: 5.7
• 作者: Zenda, Sadamoto;Matsuura, Kazuto;Asai, Masao
• 通讯作者: Asai, Masao

Impact of early radiological response evaluation on radiotherapeutic outcomes in the patients with nasal cavity and paranasal sinus malignancies.

• DOI: 10.1093/jrr/rrs021
• 发表时间: 2012-09
• 期刊: Journal of radiation research
• 影响因子: 2
• 作者: Hojo H;Zenda S;Akimoto T;Kohno R;Kawashima M;Arahira S;Nishio T;Tahara M;Hayashi R;Sasai K
• 通讯作者: Sasai K

Proton Beam Therapy for Patients with Malignancies of The Nasal Cavity, Para-nasal Sinuses, and/or Involving The Skull Base

鼻腔、鼻旁窦和/或颅底恶性肿瘤患者的质子束治疗

• 发表时间: 2011
• 作者: Shuko Abe;Koichi Ogawa;Yusuke Koike;Izumi O. Umeda;Hirofumi Fujii;櫻庭 均;S Zenda
• 通讯作者: S Zenda