Design of cochlear nerve implant based on the tonotopic organization of the cochlear nerve

基于耳蜗神经音调组织的耳蜗神经植入物设计

• 批准号: 23659789
• 负责人: KAWASE TETSUAKI
• 金额: $ 2.25万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659789/
• 关键词: 蝸牛神経インプラント; 周波数地図; 微細電極

In order to propose the ideal design of auditory nerve implant based on the physiological frequency structure of the cochlear nerve, the following three investigations were executed; i.e., (1)physiological examination on the tonotopic organization of the cochlear nerve, (2) morphological study of cochlear nerve, (3)electrophysiological examinations on the electrically evoked auditory responses using the fine bipolar stimulation. Based on the present these investigations, the wrap-like electrode wraps around the cochlear nerve with the short needle insertion electrodes were proposed as a possible design of an electrode for auditory nerve implant.

为了提出基于耳蜗神经的生理频率结构的听神经植入物的理想设计，进行了以下三项研究：（1）耳蜗神经的音调分布结构的生理学检查;（2）耳蜗神经的形态学研究;（3）电诱发听觉反应的电生理学检查。基于目前的研究，提出了将短针插入电极缠绕在耳蜗神经周围的包裹式电极作为听觉神经植入电极的可能设计。

项目成果

Electrophysiological mapping of the cochlear nucleus using the multi-channel surface microelectrodes.

使用多通道表面微电极对耳蜗核进行电生理图绘制。

• 发表时间: 2012
• 作者: Kawase T;Oda K;Yamauchi D;Hidaka H;Kobayashi T;Tetsuo Maruyama;Kawase T et al.
• 通讯作者: Kawase T et al.

Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes.

使用多通道双极表面微电极对耳蜗核进行电生理测绘。

• DOI: 10.1007/s00405-012-2077-5
• 发表时间: 2013
• 期刊: Eur Arch Otolaryngol
• 作者: Wada H;Kumano S;Murakoshi M;Koyama S;Oda K
• 通讯作者: Oda K

Current status of auditory prosthesis

听觉假体的现状

• 发表时间: 2014
• 作者: Wada H;Kumano S;Murakoshi M;Iida K;Hamana H;丸山哲夫;Kawase T
• 通讯作者: Kawase T

Electrophysiological mapping of the cochlear nucleus using the multi-channel surface microelectrodes

使用多通道表面微电极对耳蜗核进行电生理测绘

• 发表时间: 2014
• 期刊: 18th International Symposium of Tohoku University Global COE Programme Global Nano-Biomedical Engineering Education and Research Network Centre
• 作者: Kawase T;Oda K;Yamauchi D;Hidaka H;Kobayashi T
• 通讯作者: Kobayashi T

Current status of auditory prostheses

听觉假体的现状

• 发表时间: 2014
• 作者: Wada H;Kumano S;Murakoshi M;Iida K;Hamana H;丸山哲夫;Kawase T;Tetsuaki Kawase
• 通讯作者: Tetsuaki Kawase