Phosphatidylethanolamine as an organizing molecule for neurite extension
Phosphatidylethanolamine as an organizing molecule for neurite extension
批准号:
23700365
负责人:
HASEGAWA Hiroshi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
We have examined whether and how phosphatidylethanolamine, a phospholipid consisting of the plasma membrane, is involved in neuronal morphogenesis. Our results indicated that the intramembranous movement (flip-flop movement) of phosphatidylethanolamine, which is induced by a type IV ATPase, controls neurite morphogenesis by organizing actin cytoskeleton in growth cones through the regulation of small G protein Cdc42.
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Phospholipase DではなくProtein kinase Cが好中球での活性酸素産生および酵素放出に不可欠である
蛋白激酶 C(而非磷脂酶 D)对于中性粒细胞 ROS 产生和酶释放至关重要
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[K. Monobe, Y. Ishido, Y. Tohsato, et al., 佐藤 隆信]
通讯作者:
佐藤 隆信
NMDA受容体による脂質キナーゼPIP5Kの活性化は、LTDにおけるAMPA受容体のエンドサイトーシスに必須である
NMDA 受体激活脂质激酶 PIP5K 对于 LTD 中的 AMPA 受体内吞作用至关重要
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Yuki Kazayama, Takahiro Nishimura, Yusuke Ogura, Jun Tanida, 長谷川潤]
通讯作者:
長谷川潤
NMDA受容体により誘導される長期抑圧において、PI(4,5)P2 産生酵素PIP5KはAMPA受容体のエンドサイトーシスに重要である
在 NMDA 受体诱导的长期抑制过程中,产生 PI(4,5)P2 的酶 PIP5K 对于 AMPA 受体的内吞作用很重要。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hitoshi Sugisawa, Hajime Fukuda, Hirotada Mori, Masahiro Ito, Tadahiro Taniguchi, Yukako Tohsato, 鵜木隆光]
通讯作者:
鵜木隆光
Small G protein Arf6 is involved in lung homeostasis by regulating alveolar epithelial type II cell function
小G蛋白Arf6通过调节肺泡上皮II型细胞功能参与肺稳态
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[A. Terasawa, Y. Tohsato, et al., 木下雅美]
通讯作者:
木下雅美
DOI:
10.1095/biolreprod.110.089896
发表时间:
2012-05-01
期刊:
BIOLOGY OF REPRODUCTION
影响因子:
3.6
作者:
[Hasegawa, Hiroshi, Noguchi, Junko, Kanaho, Yasunori]
通讯作者:
Kanaho, Yasunori
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