Post-genomic investigation of the relict plastid and mitochondrion of malaria parasites

疟疾是一个重大的全球健康问题。 疟疾寄生虫有两个亚结构，一个残留的叶绿体和一个叶绿体，这是新的和现有的药物的极好的目标。 然而，我们不知道这两个隔间的关键功能。 整个遗传蓝图（基因组）现在可用于疟疾寄生虫，我建议确定基因组的哪些部分服务于残留的叶绿体和线粒体。 这将勾勒出他们内部运作的图景。 有了这些信息，我们可以采取理性的方法来寻找阿基里斯？疟疾的脚跟，针对寄生虫的特定药物可以开发。

Malaria is a major global health problem. The malaria parasite has two substructures, a relict chloroplast and a mitochondrion, that are excellent targets for new and existing drugs. However, we do not know the key functions of these two compartments. The entire genetic blueprint (genome) is now available for the malaria parasite and I propose to determine exactly which parts of the genome service the relict chloroplast and mitochondria. This will sketch out a picture of their inner workings. Armed with this information we can take a rational approach to seeking an Achilles? Heel of malaria against which parasite-specific drugs can be developed.