Post-genomic investigation of the relict plastid and mitochondrion of malaria parasites
Post-genomic investigation of the relict plastid and mitochondrion of malaria parasites
批准号:
DP0208165
负责人:
Prof Geoffrey McFadden
金额:
$49.62万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2002
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2002-01-01 至 2006-12-31
中文摘要
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英文摘要
Malaria is a major global health problem. The malaria parasite has two substructures, a relict chloroplast and a mitochondrion, that are excellent targets for new and existing drugs. However, we do not know the key functions of these two compartments. The entire genetic blueprint (genome) is now available for the malaria parasite and I propose to determine exactly which parts of the genome service the relict chloroplast and mitochondria. This will sketch out a picture of their inner workings. Armed with this information we can take a rational approach to seeking an Achilles? Heel of malaria against which parasite-specific drugs can be developed.
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