The Blood-Brain Barrier Transport Mechanism Controlling Analgesic Effects of Opioid Drugs in the Central Nervous System
血脑屏障转运机制控制阿片类药物在中枢神经系统的镇痛作用
基本信息
- 批准号:24590213
- 负责人:
- 金额:$ 3.49万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2012
- 资助国家:日本
- 起止时间:2012-04-01 至 2015-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Proton-Coupled Organic Cation Antiporter-Mediated Uptake of Apomorphine Enantiomers in Human Brain Capillary Endothelial Cell Line hCMEC/D3
- DOI:10.1248/bpb.b13-00773
- 发表时间:2014-02-01
- 期刊:
- 影响因子:2
- 作者:Okura, Takashi;Higuchi, Kei;Deguchi, Yoshiharu
- 通讯作者:Deguchi, Yoshiharu
Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood-brain barrier model.
- DOI:10.1186/2045-8118-10-8
- 发表时间:2013-01-26
- 期刊:
- 影响因子:7.3
- 作者:Shimomura K;Okura T;Kato S;Couraud PO;Schermann JM;Terasaki T;Deguchi Y
- 通讯作者:Deguchi Y
TRANSPORT CHARACTERISTICS OF TRAMADOL AT THE BLOOD-BRAIN BARRIER
曲马多在血脑屏障的转运特性
- DOI:
- 发表时间:2014
- 期刊:
- 影响因子:0
- 作者:Yoshiharu Deguchi;Atsushi Kitamura;Kei Higuchi;Takashi Okura
- 通讯作者:Takashi Okura
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OKURA Takashi其他文献
OKURA Takashi的其他文献
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{{ truncateString('OKURA Takashi', 18)}}的其他基金
Transport mechanisms of opioid analgesics across the blood-brain barrier
阿片类镇痛药跨血脑屏障的转运机制
- 批准号:
21790162 - 财政年份:2009
- 资助金额:
$ 3.49万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Blood-brain barrier transport of opioid agonists mediated by organic cation-sensitive transporter
有机阳离子敏感转运蛋白介导的阿片受体激动剂的血脑屏障转运
- 批准号:
19790136 - 财政年份:2007
- 资助金额:
$ 3.49万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
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Structure-function analysis of organic acid efflux transporters for efficient organic acid production
用于高效生产有机酸的有机酸流出转运蛋白的结构功能分析
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底物识别的结构要求的表征和在人血脑屏障上表达的质子/有机阳离子逆向转运蛋白分子实体的鉴定
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19K16453 - 财政年份:2019
- 资助金额:
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Grant-in-Aid for Early-Career Scientists
Study of substrates transport mechanism of organic acid exporter for efficient organic acid production via fermentation process
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17KK0148 - 财政年份:2017
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阐明人血脑屏障有机阳离子-质子交换系统的药物识别特性和分子实体
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有机酸出口商的结构和功能分析,以实现高效有机酸生产
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肠道有机阳离子转运蛋白的功能和结构分析。
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精神药物通过有机阳离子转运蛋白转移至乳汁及其对婴儿发育的影响。
- 批准号:
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有机阳离子转运蛋白作为肺癌化疗预测生物标志物的转化研究
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