Prevalence of toxic Staphylococcus aureus and levels of antibody against toxin.

有毒金黄色葡萄球菌的流行率和毒素抗体水平。

• 批准号: 24791926
• 负责人: NISHIO Akiko
• 金额: $ 2万
• 依托单位: Kanazawa Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24791926/
• 关键词: 毒素性ショック症候群; 黄色ブドウ球菌; 抗TSST-1抗体; メチシリン耐性黄色ブドウ球菌; 保菌調査

To investigate the relationship between the levels of serum antibody to staphylococcal toxic shock antigen and effect of treatment, We planned to research the prevalence of toxic shock syndrome toxin 1 (TSST-1)-producing stains of staphylococcus aureus and antibody to TSST-1 among patients with minor trauma, burns, and skin bacterial infection. Before initiation of the study, we are required to obtain approval of Ethics Committee. I re-prepared the study plan and noticed the problems with statistical analysis. I keenly realize the importance of the designing clinical research and learned the epidemiological approach to improve the quality of study.

为探讨血清金黄色葡萄球菌中毒性休克抗原抗体水平与治疗效果的关系，我们计划研究金黄色葡萄球菌中毒性休克综合征毒素1(TSST-1)菌株及其抗体在轻微创伤、烧伤和皮肤细菌感染患者中的流行情况。在开始研究之前，我们需要获得道德委员会的批准。我重新准备了学习计划，并注意到了统计分析中的问题。我敏锐地认识到设计临床研究的重要性，并学习了提高研究质量的流行病学方法。