Genomic and chromosomal evolution of vertebrates inferred from comparative gene mapping

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To deduce the process of genomic and chromosomal evolution in vertebrates, I constructed a chromosome map of Xenopus (Silurana) tropicalis using FISH mapping. The homologous segments corresponding to chicken microchromosomes have been highly conserved in X. tropicalis without microchromosomes, suggesting that the ancestral tetrapods probably had genetic linkage groups each of which corresponded to chicken microchromosomes. Next, I performed FISH mapping for an allotetraploid species, X. laevis, and constructed a comparative chromosome map between these two Xenopus species. This result indicated that the loss of duplicated genes and interchromosomal rearrangements occurred much less frequently in X. laevis allotetraploidization.