Analysis of CDV quasispecies and establishement of the reverse genetics system
Analysis of CDV quasispecies and establishement of the reverse genetics system
批准号:
24780303
负责人:
YOSHIKAWA Tomoki
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
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英文摘要
There was a canine distemper outbreak, which is generally known to be occurred in carnivore happened in the monkey colony in an animal quarantine. Hence to understand the pathogenesis, the sequences from the in vitro isolates and from these of clinical specimens were determined and analyzed by utilizing next-generation sequencing technique. In addition, establishment of the reverse genetics system based on the S-CDV sequence, which enable to produce the infectious particles from the plasmids were tried.
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DOI:
10.1371/journal.pone.0092777
发表时间:
2014
期刊:
PloS one
影响因子:
3.7
作者:
[Yamanaka A, Iwakiri A, Yoshikawa T, Sakai K, Singh H, Himeji D, Kikuchi I, Ueda A, Yamamoto S, Miura M, Shioyama Y, Kawano K, Nagaishi T, Saito M, Minomo M, Iwamoto N, Hidaka Y, Sohma H, Kobayashi T, Kanai Y, Kawagishi T, Nagata N, Fukushi S, Mizutani T, Tani H, Taniguchi S, Fukuma A, Shimojima M, Kurane I, Kageyama T, Odagiri T, Saijo M, Morikawa S]
通讯作者:
Morikawa S
DOI:
10.1186/1746-6148-8-82
发表时间:
2012-06-18
期刊:
BMC veterinary research
影响因子:
2.6
作者:
[Sayama Y, Demetria C, Saito M, Azul RR, Taniguchi S, Fukushi S, Yoshikawa T, Iizuka I, Mizutani T, Kurane I, Malbas FF Jr, Lupisan S, Catbagan DP, Animas SB, Morales RG, Lopez EL, Dazo KR, Cruz MS, Olveda R, Saijo M, Oshitani H, Morikawa S]
通讯作者:
Morikawa S
DOI:
10.1093/infdis/jit603
发表时间:
2014-03-15
期刊:
JOURNAL OF INFECTIOUS DISEASES
影响因子:
6.4
作者:
[Takahashi, Toru, Maeda, Ken, Saijo, Masayuki]
通讯作者:
Saijo, Masayuki
Canine Distemper Virus Associated with a Lethal Outbreak in Monkeys Readily Adapted to Use Human Receptors
犬瘟热病毒与易于使用人类受体的猴子的致命爆发有关
DOI:
--
发表时间:
2013
期刊:
J Virol
影响因子:
5.4
作者:
[Sakai, K. Yoshikawa, T. Seki, F. Fukushi, S. Tahara, M. Nagata, N. Ami, Y. Mizutani, T. Kurane, I. Yamaguchi, R. Hasegawa, H. Saijo, M. Komase, K. Morikawa, S. Takeda, M.]
通讯作者:
M.
IPS-1-dependent innate immune response is indispensable for limiting the SARS-CoV propagation in airway epithelial cell
IPS-1依赖性先天免疫反应对于限制SARS-CoV在气道上皮细胞中的传播是必不可少的
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Tomoki Yoshikawa, Shuetsu Fukushi, Chien-T K Tseng, Clarence J Peters]
通讯作者:
Clarence J Peters
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