Studies on the involvement in meningioma development of Neospora infection in dogs

犬新孢子虫感染参与脑膜瘤发生的研究

• 批准号: 24780308
• 负责人: ITAMOTO kazuhito
• 金额: $ 2.83万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24780308/
• 关键词: ネオスポラ; MRI; 髄膜腫; イヌ

In this study, we conducted a survey of N.caninum antibody prevalence of patients with neurological symptoms in dogs. Antibody prevalence rate of cases showed neurological symptoms were significantly higher. As a feature on MRI, Dural tail sign was observed in 21/130 cases. Between the meningioma and antibody positive rate of N.caninum that there is a relationship has been suggested. Cases of meningioma is 17 cases in pathology in Search Contact 20 surgery cases. There are the antibody positive in 15 cases. Parasite was not detected in any tissue. Those harvestable of cerebrospinal fluid retrieved in real time PCR and tissue samples five cases, in meningioma cases, but all was not obtained positive cases.

在这项研究中，我们对有神经症状的犬新城疫患者的抗体流行率进行了调查。表现为神经系统症状的病例抗体患病率明显较高。130例患者中有21例可见硬脑膜尾征。脑膜瘤与犬新城疫抗体阳性率之间存在一定的关系。脑膜瘤17例，经病理组织学检查，接触手术20例。抗体阳性15例。在任何组织中均未检测到寄生虫。那些可采集的脑脊液进行实时聚合酶链式反应和组织标本提取的5例，其中脑膜瘤病例，但均未获得阳性病例。

项目成果

VETi 抗菌薬の使いどころ (中枢神経) (6) 18-22, 2013

VETi 抗生素的使用（中枢神经系统） (6) 18-22, 2013

Enzyme-Linked Immunosorbent Assays Based on Neospora caninum Dense Granule Protein 7 and Profilin for Estimating the Stage of Neosporosis

• DOI: 10.1128/cvi.05669-11
• 发表时间: 2012-03-01
• 期刊: CLINICAL AND VACCINE IMMUNOLOGY
• 作者: Hiasa, Jun;Nishimura, Maki;Nishikawa, Yoshifumi
• 通讯作者: Nishikawa, Yoshifumi

抗菌剤の使いどころ-中枢神経

何时使用抗菌药物 - 中枢神经系统

• 发表时间: 2013
• 期刊: Vet I
• 作者: Domori A;Sunahara A;Tatemo M;Shimokawa Miyama T;Setoguchi A;Endo Y;板本和仁
• 通讯作者: 板本和仁