Effects of blood mineral levels on extracellular antioxidant defense system

血液矿物质水平对细胞外抗氧化防御系统的影响

• 批准号: 24700741
• 负责人: KAMEZAKI Fumihiko
• 金额: $ 2.83万
• 依托单位: University of Occupational and Environmental Health, Japan
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24700741/
• 关键词: ミネラル; 細胞外スーパーオキシドジスムターゼ; 酸化ストレス; 鉄; マグネシウム; 血漿ミネラル濃度

In a total of 809 middle-aged Japanese male workers, we examined the hypothesis that a decrease level of blood mineral has an important role on the dysfunction of extracellular antioxidant defense system. This study demonstrated no statistically significant correlations between blood levels of mineral such as iron and magnesium and extracellular superoxide dismutase, a major antioxidant in the cardiovascular system. Further examinations are needed to elucidate effects of blood mineral levels on the extracellular antioxidant defense system.

在总共809名日本中年男性工人中，我们检验了血液矿物质水平下降在细胞外抗氧化防御系统功能障碍中起重要作用的假设。这项研究表明，血液中铁和镁等矿物质水平与细胞外超氧化物歧化酶(心血管系统中的主要抗氧化剂)之间没有统计上的显著相关性。需要进一步的检查来阐明血液矿物质水平对细胞外抗氧化防御系统的影响。

项目成果

Reduced plasma levels of nitric oxide metabolites in normotensive middle-aged men with electrocardiographically determined left ventricular hypertrophy

心电图确定左心室肥厚、血压正常的中年男性血浆一氧化氮代谢物水平降低

• 作者: 亀崎文彦;園田信成;中田靖;樫山国宣;村岡秀崇;岡崎昌博;田村雅仁;安部治彦;竹内正明;亀崎文彦;亀崎文彦;亀崎文彦;亀崎文彦;亀崎文彦;亀崎文彦;亀崎文彦;亀崎文彦
• 通讯作者: 亀崎文彦

ICU入室中の心房細動の予防・治療

ICU住院期间房颤的预防和治疗

• 发表时间: 2014
• 期刊: INTENSIVIST
• 作者: 亀崎文彦;安部治彦;真弓俊彦
• 通讯作者: 真弓俊彦

Proposed cutoff level of waist circumference in middle-aged Japanese men : evaluation by plasma leptin levels

日本中年男性腰围的拟议临界水平：通过血浆瘦素水平进行评估

• 发表时间: 2014
• 作者: 亀崎文彦;園田信成;中田靖;樫山国宣;村岡秀崇;岡崎昌博;田村雅仁;安部治彦;竹内正明;亀崎文彦
• 通讯作者: 亀崎文彦

Plasma levels of nitric oxide metabolites are markedly reduced in normotensive individuals with electrocardiographically determined left ventricular hypertension

血压正常且经心电图确定左心室高血压的个体中一氧化氮代谢物的血浆水平显着降低

• 作者: Kamezaki F;Tsutsui M;Adachi T;Takahashi M;Sonoda S;Takeuchi M;Otsuji Y
• 通讯作者: Otsuji Y

Reduced plasma levels of nitric oxide metabolites in normo- tensive middle-aged men with electrocardiographically determined left ventricular hypertrophy

心电图确定左心室肥厚、血压正常的中年男性血浆一氧化氮代谢物水平降低

• 发表时间: 2013
• 作者: 亀崎文彦;園田信成;中田靖;樫山国宣;村岡秀崇;岡崎昌博;田村雅仁;安部治彦;竹内正明;亀崎文彦;亀崎文彦;亀崎文彦
• 通讯作者: 亀崎文彦