A role of extracellular superoxide dismutase on metabolic syndrome

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We examined a relationship between metabolic syndrome and extracellular superoxide dismutase, a major antioxidant in the cardiovascular system, in middle-aged Japanese male workers. This study demonstrated that plasma levels of extracellular superoxide dismutase were significantly increased in subjects with metabolic syndrome than in those without. This finding indicates that a therapy targeted to extracellular superoxide dismutase may be a new strategy for metabolic syndrome.