Elucidation of the transcriptional regulation of Runx2 and development of the drugs for osteoporosis and osteoarthritis
Elucidation of the transcriptional regulation of Runx2 and development of the drugs for osteoporosis and osteoarthritis
批准号:
26221310
负责人:
KOMORI Toshihisa
金额:
$124.8万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (S)
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-05-30 至 2019-03-31
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Overexpression of Sp7 in odontoblasts results in dentinogenesis imperfecta due to the inhibition of odontoblast maturation
Sp7在成牙本质细胞中过度表达,由于抑制成牙本质细胞成熟而导致牙本质发育不全
DOI:
10.1016/j.job.2017.03.003
发表时间:
2017
期刊:
Journal of Oral Biosciences
影响因子:
2.4
作者:
[Miyazaki Toshihiro, Inoue Maaya, Baba Tomomi T., Komori Toshihisa]
通讯作者:
Komori Toshihisa
ゾレドロン酸投与が骨細胞マーカー Dmp1 に及ぼす影響について
唑来膦酸给药对骨细胞标志物Dmp1的影响
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Qin X, Komori T, Yuji Kato, 社領美紀,佐藤淳,宇佐美悠,廣瀬勝俊,大家香織,小守壽文,豊澤 悟]
通讯作者:
社領美紀,佐藤淳,宇佐美悠,廣瀬勝俊,大家香織,小守壽文,豊澤 悟
PTH アナボリック作用に対する骨髄間葉系幹細胞の寄与
骨髓间充质干细胞对 PTH 合成代谢作用的贡献
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Qin X, Komori T, Yuji Kato, 社領美紀,佐藤淳,宇佐美悠,廣瀬勝俊,大家香織,小守壽文,豊澤 悟, Kodai Matsuoka, 廣瀬勝俊,宇佐美悠,佐藤淳,大家香織,小守壽文,豊澤悟, Yuji Kato, 小守 壽文, Toru Iijima, 姜晴,秦昕,小守寿人,松尾友紀,宮崎敏博,森石武史,小守壽文, 廣瀬勝俊,佐藤淳,社領美紀,野田百合,小守壽文,豊澤悟, Kenji Inami, 楊孟雨,溝口利英,宇田川信之,松尾光一,小守壽文,森石武史,小林泰浩,高橋直之]
通讯作者:
楊孟雨,溝口利英,宇田川信之,松尾光一,小守壽文,森石武史,小林泰浩,高橋直之
DOI:
10.1007/978-981-10-3233-2_6
发表时间:
2017-01-01
期刊:
RUNX PROTEINS IN DEVELOPMENT AND CANCER
影响因子:
--
作者:
[Komori, Toshihisa]
通讯作者:
Komori, Toshihisa
Runx2を利用した骨粗鬆症、変形性関節症治療薬の開発
使用 Runx2 开发骨质疏松症和骨关节炎的治疗药物
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 33 条
Elucidation of the mechanism of the regulation of Col1a1 gene expression by Runx2
-
批准号:18K19654
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2018
-
负责人:KOMORI Toshihisa
-
依托单位:
Identification of the target genes of glucocorticoid receptor in the pathogenesis of steroid-induced osteoporosis
-
批准号:16K15781
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2016
-
负责人:KOMORI Toshihisa
-
依托单位:
Elucidation of the pathogenesis of disuse osteoporosis and steroid-induced osteoporosis using Fkbp5 knockout mice
-
批准号:26670811
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2014
-
负责人:KOMORI Toshihisa
-
依托单位:
Identification and functional analysis of a novel substrate of Pdk4 in the regulation of osteoclastogenesis in the unloaded condition
-
批准号:24659829
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
-
负责人:KOMORI Toshihisa
-
依托单位:
The molecule mechanism of the bone mass regulation by a bone cell network
-
批准号:22659331
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.05万
-
财政年份:2010
-
负责人:KOMORI Toshihisa
-
依托单位:
The mechanism of transcriptional regulation of Runx2 gene and the program of skeletal development
-
批准号:22249062
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.37万
-
财政年份:2010
-
负责人:KOMORI Toshihisa
-
依托单位:
Elucidation of the mechanism of skeletal development using Runx2 and Cbfb conditional knockout mice
-
批准号:19390465
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.31万
-
财政年份:2007
-
负责人:KOMORI Toshihisa
-
依托单位:
Elucidation of the interaction between Akt and Runx2 in the regulation of cell size, chemotaxis, and differentiation of skeletal component cells
-
批准号:15370087
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.86万
-
财政年份:2003
-
负责人:KOMORI Toshihisa
-
依托单位:
海外基金