Elucidation of the pathogenesis of disuse osteoporosis and steroid-induced osteoporosis using Fkbp5 knockout mice
Elucidation of the pathogenesis of disuse osteoporosis and steroid-induced osteoporosis using Fkbp5 knockout mice
批准号:
26670811
负责人:
KOMORI Toshihisa
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2016-03-31
中文摘要
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英文摘要
期刊论文(33)
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DOI:
10.1007/s00441-015-2135-6
发表时间:
2015-08-01
期刊:
CELL AND TISSUE RESEARCH
影响因子:
3.6
作者:
[Miyazaki, Toshihiro, Baba, Tomomi T., Komori, Toshihisa]
通讯作者:
Komori, Toshihisa
Cbfb plays important roles in bone development through the stabilization of Run family proteins.
Cbfb 通过稳定 Run 家族蛋白在骨骼发育中发挥重要作用。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Qin X,Jiang Q,Matsuo Y,Kawane T,Komori H,Moriishi T,Taniuchi I, Ito K,Kawai Y,Rokutanda S,Izumi S, Komori T.]
通讯作者:
Komori T.
Bcl-2ノックアウトマウスではAktの不活性化によりFoxOが活性化し、骨芽細胞分化が促進する
在 Bcl-2 敲除小鼠中,Akt 失活会激活 FoxO 并促进成骨细胞分化。
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[森石 武史, 小守 寿人, 小守 壽文]
通讯作者:
小守 壽文
DOI:
10.1002/jcp.24823
发表时间:
2015-04
期刊:
Journal of Cellular Physiology
影响因子:
5.6
作者:
[Takashi Nakamura;M. Naruse;Y. Chiba;T. Komori;K. Sasaki;M. Iwamoto;S. Fukumoto]
通讯作者:
Takashi Nakamura;M. Naruse;Y. Chiba;T. Komori;K. Sasaki;M. Iwamoto;S. Fukumoto
Runx2遺伝子の骨芽細胞特異的発現制御機構
Runx2基因的成骨细胞特异性表达调控机制
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[小守 寿人, 川根 哲也, 森石 武史, 高田 美生, 小守 壽文]
通讯作者:
小守 壽文
共 13 条
Elucidation of the mechanism of the regulation of Col1a1 gene expression by Runx2
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批准号:18K19654
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2018
-
负责人:KOMORI Toshihisa
-
依托单位:
Identification of the target genes of glucocorticoid receptor in the pathogenesis of steroid-induced osteoporosis
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批准号:16K15781
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2016
-
负责人:KOMORI Toshihisa
-
依托单位:
Elucidation of the transcriptional regulation of Runx2 and development of the drugs for osteoporosis and osteoarthritis
-
批准号:26221310
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$124.8万
-
财政年份:2014
-
负责人:KOMORI Toshihisa
-
依托单位:
Identification and functional analysis of a novel substrate of Pdk4 in the regulation of osteoclastogenesis in the unloaded condition
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批准号:24659829
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
-
负责人:KOMORI Toshihisa
-
依托单位:
The molecule mechanism of the bone mass regulation by a bone cell network
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批准号:22659331
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.05万
-
财政年份:2010
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负责人:KOMORI Toshihisa
-
依托单位:
The mechanism of transcriptional regulation of Runx2 gene and the program of skeletal development
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批准号:22249062
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.37万
-
财政年份:2010
-
负责人:KOMORI Toshihisa
-
依托单位:
Elucidation of the mechanism of skeletal development using Runx2 and Cbfb conditional knockout mice
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批准号:19390465
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.31万
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财政年份:2007
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负责人:KOMORI Toshihisa
-
依托单位:
Elucidation of the interaction between Akt and Runx2 in the regulation of cell size, chemotaxis, and differentiation of skeletal component cells
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批准号:15370087
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.86万
-
财政年份:2003
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负责人:KOMORI Toshihisa
-
依托单位:
海外基金