Elucidating the mechanisms underlying epithelial cell height change mediated by modifications of apical-basal polarity

阐明顶端-基底极性改变介导的上皮细胞高度变化的机制

• 批准号: 15H04373
• 负责人: Wang Yuchiun
• 金额: $ 10.32万
• 依托单位: Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04373/
• 关键词: Epithelial folding; Apical-basal polarity; Microtubule mechanics; microtubule forces; Patronin/CAMSAP; cell shortening; size homeostasis; apical-basal polarity; microtubule network; cell shape control; epithelial folding; epithelial cell height

项目成果

Cell shortening for epithelial folding via a polarity-coupled, homeostatic microtubule scaffold

通过极性耦合、稳态微管支架缩短细胞以实现上皮折叠

• 发表时间: 2017
• 作者: Yu-Chiun Wang

Epithelial origami: cell polarity, adhesion mechanics, and the folding of epithelial tissues

上皮折纸：细胞极性、粘附力学和上皮组织的折叠

• 发表时间: 2015
• 作者: Yu-Chiun Wang

Force (im)balance during homeostatic and transformative states of epithelial folding

上皮折叠稳态和转化状态期间的力（不）平衡

• 发表时间: 2018
• 作者: Fukuda;M.;Yu-Chiun Wang
• 通讯作者: Yu-Chiun Wang

A homeostatic apical microtubule network shortens cells for epithelial folding via a basal polarity shift

• DOI: 10.1038/s41556-017-0001-3
• 发表时间: 2017-12
• 期刊: Nature Cell Biology
• 影响因子: 21.3
• 作者: Michiko Takeda;M. M. Sami-M.;Yu-Chiun Wang

Epithelial origami: homeotic microtubule network coupled to apical-basal polarity propels cell shortening during epithelial folding

上皮折纸：与顶底极性耦合的同源微管网络在上皮折叠过程中推动细胞缩短

• 发表时间: 2016
• 作者: Yu-Chiun Wang