Mogamulizumab induced immune related adverse events; the impact of Treg depletion

Mogamulizumab 诱导免疫相关不良事件；

• 批准号: 16H04713
• 负责人: ISHIDA TAKASHI
• 金额: $ 10.73万
• 依托单位: Iwate Medical University (2017-2018)Nagoya City University (2016)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H04713/
• 关键词: CCR4; 制御性T細胞; 免疫関連有害事象; 自己抗体; 成人T細胞白血病; モガムリズマブ; Treg; autoimmunity; mogamulizumab; 腫瘍治療学; 抗体療法

项目成果

Cyclin-dependent kinase 9 is a novel specific molecular target in adult T-cell leukemia/lymphoma

• DOI: 10.1182/blood-2016-09-741983
• 发表时间: 2017-08-31
• 期刊: BLOOD
• 影响因子: 20.3
• 作者: Narita, Tomoko;Ishida, Takashi;Iida, Shinsuke
• 通讯作者: Iida, Shinsuke

Effects of first-line chemotherapy on natural killer cells in adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma.

• DOI: 10.1007/s00280-016-3070-2
• 发表时间: 2016-07
• 期刊: Cancer chemotherapy and pharmacology
• 影响因子: 3
• 作者: Ogura M;Ishida T;Tsukasaki K;Takahashi T;Utsunomiya A
• 通讯作者: Utsunomiya A

Pre- and post-transplant ponatinib for a patient with acute megakaryoblastic blast phase chronic myeloid leukemia with T315I mutation who underwent allogeneic hematopoietic stem cell transplantation

• DOI: 10.1007/s12185-019-02628-8
• 发表时间: 2019-07-01
• 期刊: INTERNATIONAL JOURNAL OF HEMATOLOGY
• 影响因子: 2.1
• 作者: Sasaki, Hirokazu;Mitani, Sachiko;Iida, Shinsuke
• 通讯作者: Iida, Shinsuke

Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report

• DOI: 10.1200/jco.18.00501
• 发表时间: 2019-03-10
• 期刊: JOURNAL OF CLINICAL ONCOLOGY
• 影响因子: 45.3
• 作者: Cook, Lucy B.;Fuji, Shigeo;Watanabe, Toshiki
• 通讯作者: Watanabe, Toshiki

Cognitive dysfunction among newly diagnosed older patients with hematological malignancy: frequency, clinical indicators and predictors

新诊断老年血液恶性肿瘤患者的认知功能障碍：频率、临床指标和预测因素

• DOI: 10.1093/jjco/hyx159
• 发表时间: 2018
• 期刊: Japanese Journal of Clinical Oncology
• 影响因子: 2.4
• 作者: Aiki Sayo;Okuyama Toru;Sugano Koji;Kubota Yosuke;Imai Fuminobu;Nishioka Masahiro;Ito Yoshinori;Iida Shinsuke;Komatsu Hirokazu;Ishida Takashi;Kusumoto Shigeru;Akechi Tatsuo
• 通讯作者: Akechi Tatsuo