The development of novel treatment strategies for ATL patients by mogamulizumab

mogamulizumab 开发 ATL 患者新治疗策略

• 批准号: 25290058
• 负责人: ISHIDA TAKASHI
• 金额: $ 10.98万
• 依托单位: Nagoya City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25290058/
• 关键词: CCR4; 制御性T細胞; 成人T細胞白血病/リンパ腫; IDO; mogamulizumab; 成人T細胞白血病リンパ腫; ATL; HTLV-1; Tax

项目成果

The Efficacy and Safety of Mogamulizumab (KW-0761) in Multicenter Phase II Study for Patients with Relapsed Peripheral or Cutaneous T-Cell Lymphoma

Mogamulizumab (KW-0761) 在针对复发性外周或皮肤 T 细胞淋巴瘤患者的多中心 II 期研究中的疗效和安全性

• 发表时间: 2013
• 作者: Ueda R;Ogura M;Ishida T;Hatake K;Taniwaki M;Ando K;Tobinai K;Fujimoto K;Yamamoto K;Miyamoto T;Uike N;Tanimoto M;Tsukasaki K;Ishizawa K;Suzumiya J;Inagaki H;Tamura K;Akinaga S;Tomonaga M.
• 通讯作者: Tomonaga M.

Multicenter phase II study of mogamulizumab (KW-0761), a defucosylated anti-CCR4 antibody, in patients with relapsed peripheral T-cell lymphoma and cutaneous T-cell lymphoma.

mogamulizumab (KW-0761)（一种去岩藻糖基化抗 CCR4 抗体）在复发性外周 T 细胞淋巴瘤和皮肤 T 细胞淋巴瘤患者中的多中心 II 期研究。

• 发表时间: 2014
• 期刊: J Clin Oncol.
• 作者: 7.Ogura M*;Ishida T*;Hatake K;Taniwaki M;Ando K;Tobinai K;Fujimoto K;Yamamoto K;Miyamoto T;Uike N;Tanimoto M;Tsukasaki K;Ishizawa K;Suzumiya J;Inagaki H;Tamura K;Akinaga S;Tomonaga M;Ueda R.
• 通讯作者: Ueda R.

Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model

贝伐珠单抗在微环境依赖性成人 T 细胞白血病/淋巴瘤小鼠模型中的抗肿瘤作用

• DOI: 10.1111/ejh.12231
• 发表时间: 2014
• 期刊: European Journal of Haematology
• 影响因子: 3.1
• 作者: Mori F;Ishida T;Ito A;Sato F;Masaki A;Narita T;Suzuki S;Yamada T;Takino H;Ri M;Kusumoto S;Komatsu H;Hishizawa M;Imada K;Takaori-Kondo A;Niimi A;Ueda R;Inagaki H;Iida S
• 通讯作者: Iida S

Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma

• DOI: 10.1158/1078-0432.ccr-14-2275
• 发表时间: 2015-06-15
• 期刊: CLINICAL CANCER RESEARCH
• 影响因子: 11.5
• 作者: Masaki, Ayako;Ishida, Takashi;Iida, Shinsuke
• 通讯作者: Iida, Shinsuke

Multicenter Phase II Study of Lenalidomide in Patients with Relapsed Adult T-Cell Leukemia-Lymphoma

来那度胺治疗复发性成人 T 细胞白血病-淋巴瘤患者的多中心 II 期研究

• 发表时间: 2015
• 作者: Fujiwara H;Ishida T;Nosaka K;Taira N;Abe Y;Imaizumi Y;Moriuchi Y;Jo T;Ishizawa K;Tobinai K;Tsukasaki K;Ito S;Yoshimitsu M;Otsuka M;Ogura M;Midorikawa S;Ruiz W;Ohtsu T,
• 通讯作者: Ohtsu T,