TSP-1 expression of hepatocellular carcinoma in recurrence and metastasis after hepatectomy: the mechanism and therapeutic strategy.

肝细胞癌肝切除术后复发转移中TSP-1的表达：机制及治疗策略

• 批准号: 17K10670
• 负责人: Kuroki Hideyuki
• 金额: $ 3万
• 依托单位: Kumamoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2020-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K10670/
• 关键词: 肝細胞癌; Thrombospondin 1; sorafenib; p38 MAP kinase; SB203580; 肝切除術; 肝再生; TSP-1; HCC; Hepatectomy; TGF-β; Sorafenib; LSKL peptide

项目成果

肝再生および肝萎縮におけるトロンボスポンディン1の役割解明と臨床応用への探索

阐明血小板反应蛋白1在肝再生和肝萎缩中的作用并寻求临床应用

• 发表时间: 2017
• 作者: 林洋光;黒木秀幸;東孝暁;武山秀晶;岡部弘尚;今井克憲;山下洋市;高森啓史;馬場秀夫
• 通讯作者: 馬場秀夫

Is disease progression a contraindication for the strategy of portal vein embolization followed by hepatectomy for hepatocellular carcinoma?

• DOI: 10.1016/j.surg.2018.10.023
• 发表时间: 2019-04-01
• 期刊: SURGERY
• 影响因子: 3.8
• 作者: Imai, Katsunori;Yamashita, Yo-ichi;Baba, Hideo
• 通讯作者: Baba, Hideo

Hepatic Resection Followed by Hepatic Arterial Infusion Chemotherapy for Hepatocellular Carcinoma with Intrahepatic Dissemination

• DOI: 10.21873/anticanres.12254
• 发表时间: 2018-01-01
• 期刊: ANTICANCER RESEARCH
• 影响因子: 2
• 作者: Kuramoto, Kunitaka;Beppu, Toru;Baba, Hideo
• 通讯作者: Baba, Hideo

Thrombospondin-1 expression may be implicated in liver atrophic mechanism due to obstructed portal venous flow.

Thrombospondin-1 表达可能与门静脉血流阻塞导致的肝脏萎缩机制有关。

• DOI: 10.1111/hepr.12792
• 发表时间: 2016
• 期刊: Hepatol Res
• 影响因子: 4.2
• 作者: Hayashi H;Kuroki H;Higashi T;Takeyama H;Yokoyama N;Okabe H;Nitta H;Beppu T;Takamori H;Baba H.
• 通讯作者: Baba H.

Prognostic value of LINE-1 methylation level in 321 patients with primary liver cancer including hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

• DOI: 10.18632/oncotarget.25124
• 发表时间: 2018-04-17
• 期刊: Oncotarget
• 作者: Miyata T;Yamashita YI;Baba Y;Harada K;Yamao T;Umezaki N;Tsukamoto M;Kitano Y;Yamamura K;Arima K;Nakagawa S;Okabe H;Imai K;Hashimoto D;Chikamoto A;Shimokawa M;Baba H
• 通讯作者: Baba H