Development of a novel treatment strategy to protect vascular endothelial cells with TM mutant

开发一种新的治疗策略来保护TM突变体血管内皮细胞

• 批准号: 18H02844
• 负责人: Ikezoe Takayuki
• 金额: $ 6.82万
• 依托单位: Fukushima Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02844/
• 关键词: トロンボモジュリン; 血管内皮細胞; thrombomodulin; SOS; transplantation

项目成果

Stimulation of GPR15 on vascular endothelial cells mediates angiogenesis and cytoprotective function

GPR15 对血管内皮细胞的刺激介导血管生成和细胞保护功能

• 发表时间: 2019
• 作者: Masahiko Fukatsu;Xintao Wang ;Lobna Alkebsi;Hiroshi Ohkawara;Goichi Honda;Takayuki Ikezoe.
• 通讯作者: Takayuki Ikezoe.

Clinical effects of recombinant thrombomodulin and defibrotide on sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation

• DOI: 10.1038/s41409-018-0304-4
• 发表时间: 2019-05-01
• 期刊: BONE MARROW TRANSPLANTATION
• 影响因子: 4.8
• 作者: Yakushijin, Kimikazu;Ikezoe, Takayuki;Fukuda, Takahiro
• 通讯作者: Fukuda, Takahiro

Management of transplant-associated thrombotic microangiopathy

移植相关血栓性微血管病的治疗

• DOI: 10.11406/rinketsu.59.2307
• 发表时间: 2018
• 期刊: Rinsho Ketsueki
• 作者: Harada-Shirado K;Wang X;Mori H;Fukatsu M;Takahashi H;Shichishima-Nakamura A;Kimura S;Ohkawara H;Yamada S;Ito T;Ikezoe T.;Ikezoe T;池添 隆之
• 通讯作者: 池添 隆之

出血傾向を主訴に来院した高齢患者への対応

以出血倾向为主诉就诊的老年患者的治疗

• 发表时间: 2019
• 作者: Miki Furukawa;Wang Xintao;Hiroshi Ohkawara;Masahiko Fukatsu;Lobna Alkebsi;Hideyoshi Noji;Kazuei Ogawa;Takayuki Ikezoe;池添隆之;池添隆之
• 通讯作者: 池添隆之

Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors

健康供体中高剂量粒细胞集落刺激因子募集的外周血祖细胞有效动员的单采最佳时机

• DOI: 10.1016/j.transci.2020.102737
• 发表时间: 2020
• 期刊: Transfusion and Apheresis Science
• 影响因子: 1.9
• 作者: Kimura Satoshi;Ohkawara Hiroshi;Minakawa Keiji;Fukatsu Masahiko;Mori Hirotaka;Takahashi Hiroshi;Harada-Shirado Kayo;Ohara Yoshihiro;Takahashi Nobuhisa;Mochizuki Kazuhiro;Sano Hideki;Nollet Kenenth E;Ogawa Kazuei;Ohto Hitoshi;Kikuta Atsushi;Ikeda Kazuhiko
• 通讯作者: Ikeda Kazuhiko