GRK 1508: Arterial Remodelling

心血管研究培训集团EuCAR建立在一个接近（不到30公里）的独特资产和RWTH亚琛和马斯特里赫特大学之间广泛和互补的双边合作网络的坚实基础上。鉴于心血管疾病对西方社会发病率和死亡率的巨大意义及其对公共卫生经济的影响，EuCAR研究计划侧重于基础的大血管病理生物学和病理生理学，即动脉重塑，动脉粥样硬化及其炎症成分。主要目标是引入来自相关领域的高度相关的新的细胞和分子靶标，例如免疫介质和生长因子。这与DFG研究单位809（心血管发病机制中的趋化因子和粘附分子）和专门的心血管研究所马斯特里赫特（CARIM）认可的科学环境非常一致。重点放在申请人的最佳选择上，其特点是高度引用的出版物的平衡记录，以及在该领域发表多篇论文的杰出博士，医学博士/博士或医学博士毕业生的近期历史，以及为博士生或博士后提供大量资金，以补充研究培训小组。每个项目将由至少一名来自亚琛和一名来自马斯特里赫特的申请人指导，这将不仅形成一个共享的论文委员会，但将包括一个成功的任期非等级参与-跟踪助理，对毕业生进行密切和综合的指导和监督，并向指导委员会报告。招聘过程将包括国际DFG办公室，最初的客座奖学金和面试过程，以评估个人背景，并确定个人资格简介，并参与推荐的模块。教学计划不仅基于两个专栏，亚琛和CARIM的博士课程，而且还将实施特定的模块和软技能培训，并将通过大师班，讲座系列，国际年度研讨会会议以及助理指导和研究生组织的活动横向互连，例如电子学习方法和虚拟显微镜平台。对于评估和双学位成功毕业，将实施学分制和高级出版要求标准，这些标准沿着DFG卓越倡议期间在RWTH开设的博士研究中心的指导方针。

The Cardiovascular Research Training Group EuCAR builds on the unique asset of a close proximity (less than 30 km) and the solid foundation of an extensive and complementary network of bilateral collaborations between the RWTH Aachen and Maastricht Universities. Given the enormous significance of cardiovascular disease for the morbidity and mortality in western societies and its impact on public health economy, the EuCAR research programme is focussed on the underlying macrovascular pathobiology and pathophysiology, namely arterial remodelling, atherosclerosis and its inflammatory components. A main goal is to introduce novel cellular and molecular targets of high relevance from related fields, e.g. immune mediators and growth factors. This is in excellent accordance with the scientific environment endorsed by the DFG Research Unit 809 (Chemokines and Adhesion Molecules in Cardiovascular Pathogenesis) and the dedicated Cardiovascular Research Institute Maastricht (CARIM). Emphasis is placed on optimal selection of applicants, which feature a well-balanced record of highly cited publications and evenly matched recent history of outstanding PhD, MD/PhD or MD graduates with multiple publications in the field, and a plethora of funding for PhD students or post-docs complementing the Research Training Group.In a strictly bilateral approach, each project will be guided by at least one applicant from Aachen and one from Maastricht, which will not only form a shared thesis committee but will include a non-hierarchical involvement of successful tenure-track assistants for close and integrative mentoring and supervision of graduates and reports to the steering committee. The recruitment process will encompass international DFG offices, initial guest scholarships and an interview process to assess individual backgrounds and to define individual qualifying profiles with participation in recommended modules. The teaching programme is not only based on two columns, the PhD programme in Aachen and at CARIM, but will also implement specific modules and soft skill training, and will be horizontally interlinked by master classes, lecture series, international annual workshop meetings, as well as assistant-guided and graduate-organised activities, e.g. an eLearning methods and virtual microscopy platform. For evaluation and successful graduation with a double degree, a credit point system and advanced publication requirement criteria will be imposed, which are oriented along the guidelines for the Centre for Doctorate Studies inaugurated at the RWTH during the DFG Excellence initiative.