An Attempt to Propose Prescription for Hemodialysis Treatment Using Neural Network Machine Learning.

尝试使用神经网络机器学习提出血液透析治疗处方。

• 批准号: 22K07426
• 负责人: 菅野 厚博
• 金额: $ 0.58万
• 依托单位: Tohoku Medical and Pharmaceutical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2022
• 资助国家: 日本
• 起止时间: 2022-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K07426/
• 关键词: 機械学習; ニューラルネットワーク; 血液透析; 処方提案

本研究は以下に記す、①～③のフェーズを要する。各段階の進捗については以下の通り。①血液透析濾過を施行中の患者からのデータ集積、データシート作成：初年度は血液透析濾過治療を行っている患者を対象に解析を行う。・現在は対象となる血液透析患者の選定、基礎特性ならびに特にカルシウム、リンに関連する、いわゆるCKD-MPD関連の検査値の推移、リン吸着薬などの内服薬などの背景を確認し、解析の基礎となるデータマイニングを行っている。現在はこれらのデータマイニングを継続している状況である。そのため、Mathematicaでのプログラム作成にまでは達していないのが現状。②ニューラルネットワークに機械学習させ検証を行う：これをもとにいずれの処方が現実的に選択されたかについて数理計算ソフトMathematicaに学習させる。・データの選択が完了しておらず、現時点では着手するに至っていない。③教育の精度を確認し、外れ値について考察する：ニューラルネットワークでの予測値と実測値とを比較させる。・今回の研究で最も労力が傾注されるべきポイントであるが同様の理由で着手できていない。以上から、今後②へいかに早期に移行できるかが今後の研究の分岐点となるものと考えられる。これとは別に対象者へは同クリニック内の掲示物によるオプトアウトにて参加への不同意があった場合にはその旨を申告頂くようにしている。

In this study, the following notes are recorded, and 1-3-year-old records are required. The following information is required for each paragraph. The main results are as follows: (1) during the implementation of hemodialysis, the patients were divided into two groups: in the beginning of the year, the patients were treated by hemodialysis. Now that the basic characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, the characteristics of hemodialysis patients have been selected, and their characteristics have been selected. At present, there is a situation in which there is no problem. If you don't know what to do, the Mathematica will tell you what to do, and then you will have to do something like that. 2. In the field of mechanical engineering, the selection of mathematical and physical calculations is based on the selection of Mathematica computers. When you are done, start to do so at some point in time. (3) the accuracy of education should be confirmed, and the accuracy of the test should be compared with each other. This time, the most important thing in this study is to start the study for the same reason. The above, the next two years, early migration, future research, bifurcation points, bifurcation points, research points, bifurcation points, and so on. If you don't agree with each other, you may wish to declare that you don't agree with each other.

项目成果

Cross-classification by systolic and diastolic blood pressure levels and chronic kidney disease, proteinuria, or kidney function decline

按收缩压和舒张压水平与慢性肾脏病、蛋白尿或肾功能下降进行交叉分类

• DOI: 10.1038/s41440-023-01267-1
• 发表时间: 2023
• 期刊: Hypertension Research
• 影响因子: 5.4
• 作者: Suenaga Tsukasa;Satoh Michihiro;Murakami Takahisa;Hirose Takuo;Obara Taku;Nakayama Shingo;Hashimoto Hideaki;Toyama Maya;Muroya Tomoko;Kanno Atsuhiro;Mori Takefumi;Ohkubo Takayoshi;Imai Yutaka;Metoki Hirohito
• 通讯作者: Metoki Hirohito

Significant dysphagia and abdominal distension were caused by central adrenal insufficiency in an elderly man

一名老人因中枢性肾上腺皮质功能不全而出现严重吞咽困难和腹胀

• DOI: 10.1111/ggi.14587
• 发表时间: 2023
• 期刊: Geriatr Gerontol Int .
• 作者: Atsuhiro Kanno;Katsutoshi Furukawa;et al.
• 通讯作者: et al.