Targetable (Epi)Genetic, Physiological and Neuroimaging Risk Markers of Anxiety Sensitivity: A Developmental, Cross-Disorder Prevention Study of Separation Anxiety and Panic Disorder (C02)

在一个多水平模型的焦虑症在整个生命周期，环境和（epi）遗传因素以及生理和神经网络标志物在二氧化碳（CO2）的挑战将被调查的潜力作为预测和/或介质的预防性干预沿着焦虑敏感性/分离焦虑/惊恐障碍谱。所确定的风险标志物预计将有助于一个有针对性的预测风险标志物面板通知未来指示，从而更有效的预防措施焦虑症。

In a multi-level model of anxiety disorders across the life-span, environmental and (epi)genetic factors as well as physiological and neural network markers during a carbon dioxide (CO2) challenge will be investigated for their potential as predictors and/or mediators of a preventive intervention along the anxiety sensitivity/separation anxiety/panic disorder spectrum. The identified risk markers are expected to contribute to a targetable predictive risk marker panel informing future indicated and thus even more effective preventive measures for anxiety disorders.