Pathogenesis and treatment of gonarthrosis spatial aspect on the thrust of osteoarthritic knees.

在行走时对正常和骨关节炎膝关节进行加速度计和足部压力分析。研究发现，外侧抬高的楔形鞋垫可以降低外侧加速度的大小，同时增加足压力中心的内侧长度。因此，鞋垫被证明是有效的保守治疗内侧间室CA膝关节。然而，当根据生物力学和放射学阶段分析鞋垫的治疗效果时，使用这种鞋垫疗法被证明在基础患者中较少。因此，这些发现表明鞋垫疗法并不适用于所有的个体。我们通过关节声音来评估透明质酸对严重骨关节炎的影响。受试者为40例终末期OA患者的40个膝关节（8例男性，32例女性），平均年龄66.7岁。HA给药一次。在注射到膝关节之前和之后，我们在弯曲和拉伸关节的同时测量了5次关节音。用Bruel & Kjaer4189型传声器记录声音，输入双通道分析仪，进行快速傅立叶变换频谱分析。HA给药前的平均频率为422.5*68.9Hz，给药后即刻为219.4*22.9Hz，表明频率显著降低。对照组给药后未见显著差异。说明关节内注射HA具有润滑作用。

Accelerometric and foot pressure analyses were performed on normal and osteoarthritic knees while walking. A laterally elevated wedged-insole was found to decreasa the magnitude of the lateral accelcration while increasing the medial length of the center of foot pressure. The insole thus proved effective for the conservative treatment of the medial compartment CA knees. However, when analyzing the therapeutic efficacy of the insole according to the biomechanical and radiographic stage, use of such insole therapy proved to be less in obase patients. These findings thus suggest that insole therapy is not appliciable to all individuals.We evaluated the effect of hyaluronic acid on severe osteoarthritis by joint sound. The subjects were 40 knees of 40 end stage OA patients (8 male, 32 female) with a mean age of 66.7 years. HA was administered to them once. Before and after the injection into the knee joint, we measured joint sounds 5 times while bending and stretcing the joint. The sound were recorded by Bruel & Kjaer 4189 type microphones and input into a 2 channel analysis device, and then the fast fourier transformed frequency spectru** was analyzed. The mean frequency before HA administration was 422.5*68.9Hz, and 219.4*22.9Hz immediately after, indicating a significant decrease in frequency. There was no significant difference seen in the control group after administration. This showed that injection of HA in to the knee joint had a lubricating function.